Measurements on the diffusion coefficient of colloidal particles by Taylor-Aris dispersion

B. M. Belongia, James C Baygents

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Taylor-Aris dispersion in narrow-bore capillaries is used to measure the diffusion coefficient of colloidal particles in aqueous suspension. The method is shown to yield accurate results for particles up to about 0.3 μm in diameter; the measurement time for larger particles is prohibitively long and impractical. For hydrophobic particles, interactions with the capillary walls can introduce error into the interpretation of the data. The measurements also suggest that buoyancy-driven particle motion can introduce error. Consequently, a method similar to capillary hydrodynamic fractionation was developed to establish when these factors were of negligible effect. The results constitute an order-and-a-half improvement in the sensitivity of the technique, which has been recently shown to work for nanometer-sized proteins. The data suggest that, when matched with the appropriate theory, dispersion in capillaries may be a useful probe of colloidal and gravitational interaction potentials.

Original languageEnglish (US)
Pages (from-to)19-31
Number of pages13
JournalJournal of Colloid and Interface Science
Volume195
Issue number1
DOIs
StatePublished - Nov 1 1997

Fingerprint

diffusion coefficient
Particle interactions
Fractionation
Time measurement
Buoyancy
Suspensions
Hydrodynamics
Proteins
particle motion
particle interactions
buoyancy
fractionation
hydrodynamics
time measurement
proteins
cavities
probes
sensitivity
interactions

Keywords

  • Brownian motion
  • Capillary electrophoresis
  • Capillary hydrodynamic fractionation
  • Colloidal dispersions

ASJC Scopus subject areas

  • Colloid and Surface Chemistry
  • Physical and Theoretical Chemistry
  • Surfaces and Interfaces

Cite this

Measurements on the diffusion coefficient of colloidal particles by Taylor-Aris dispersion. / Belongia, B. M.; Baygents, James C.

In: Journal of Colloid and Interface Science, Vol. 195, No. 1, 01.11.1997, p. 19-31.

Research output: Contribution to journalArticle

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