Measuring the acoustoelectric interaction constant in cardiac tissue using ultrasound current source density imaging

Qian Li, Ragnar Olafsson, Pier Ingram, Zhaohui Wang, Russell S Witte

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

This paper demonstrates the first measurement of the acoustoelectric (AE) interaction constant in cardiac tissue. Radiofrequency catheter ablation is performed in clinics as a standard treatment for cardiac arrhythmia with a high success rate. The procedure requires a detailed map of the heart's activation wave prior to treatment. Conventional electrical mapping techniques are slow, prone to registration errors and have limited spatial resolution. We have developed Ultrasound Current Source Density Imaging (UCSDI) as a new modality to map reentry currents in the heart. UCSDI is based on the AE effect and Ohm's Law. The AE effect states that ultrasound pressure can be converted to a change in resistivity. The conversion efficiency is determined by the AE interaction constant K, a fundamental property of all materials; it directly affects the magnitude of the detected signals in UCSDI. In this study, K was measured in rabbit heart tissue, NaCl and CuSO4 solution with UCSDI. A custom chamber was fabricated to control the geometry for estimating K. A 1 MHz transducer was pulsed at 200 Hz to induce a local and transient modulation of resistivity. K was calculated to be 0.0430.013%/MPa in the heart based on the AE signal recorded with UCSDI. The value of K was in range of 0.9% NaCl. This provides a baseline estimate of K for mapping reentry currents in the heart with UCSDI.

Original languageEnglish (US)
Title of host publicationProceedings - IEEE Ultrasonics Symposium
Pages245-248
Number of pages4
DOIs
StatePublished - 2010
Event2010 IEEE International Ultrasonics Symposium, IUS 2010 - San Diego, CA, United States
Duration: Oct 11 2010Oct 14 2010

Other

Other2010 IEEE International Ultrasonics Symposium, IUS 2010
CountryUnited States
CitySan Diego, CA
Period10/11/1010/14/10

Fingerprint

interactions
reentry
arrhythmia
electrical resistivity
rabbits
ablation
transducers
estimating
spatial resolution
chambers
activation
modulation
estimates
geometry

Keywords

  • acoustoelectric
  • cardiac arrhythmia
  • interaction constant

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Li, Q., Olafsson, R., Ingram, P., Wang, Z., & Witte, R. S. (2010). Measuring the acoustoelectric interaction constant in cardiac tissue using ultrasound current source density imaging. In Proceedings - IEEE Ultrasonics Symposium (pp. 245-248). [5935998] https://doi.org/10.1109/ULTSYM.2010.5935998

Measuring the acoustoelectric interaction constant in cardiac tissue using ultrasound current source density imaging. / Li, Qian; Olafsson, Ragnar; Ingram, Pier; Wang, Zhaohui; Witte, Russell S.

Proceedings - IEEE Ultrasonics Symposium. 2010. p. 245-248 5935998.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Li, Q, Olafsson, R, Ingram, P, Wang, Z & Witte, RS 2010, Measuring the acoustoelectric interaction constant in cardiac tissue using ultrasound current source density imaging. in Proceedings - IEEE Ultrasonics Symposium., 5935998, pp. 245-248, 2010 IEEE International Ultrasonics Symposium, IUS 2010, San Diego, CA, United States, 10/11/10. https://doi.org/10.1109/ULTSYM.2010.5935998
Li, Qian ; Olafsson, Ragnar ; Ingram, Pier ; Wang, Zhaohui ; Witte, Russell S. / Measuring the acoustoelectric interaction constant in cardiac tissue using ultrasound current source density imaging. Proceedings - IEEE Ultrasonics Symposium. 2010. pp. 245-248
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