Mechanism of action of retinyl compounds on wound healing I: Structural relationship of retinyl compounds and wound healing

K. H. Lee, Theodore G. Tong

Research output: Contribution to journalArticle

13 Scopus citations


Retinol, retinyl acetate, and retinoic acid promote wound healing. Retinoic acid is most active. Beta‐carotene is active, while lycopene is inactive; β‐ionone is active and α‐ionone is inactive. For full activity, the compound should contain a β‐ionone ring, a conjugated double‐bond side chain, and a terminal carboxylic acid side chain.

Original languageEnglish (US)
Pages (from-to)851-854
Number of pages4
JournalJournal of pharmaceutical sciences
Issue number6
StatePublished - Jun 1970
Externally publishedYes



  • GLC—separation
  • NMR spectroscopy—identity
  • Retinyl compounds, activity—structural relationship
  • Wound healing—retinyl compound effect

ASJC Scopus subject areas

  • Pharmaceutical Science

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