Mechanism of action of retinyl compounds on wound healing II: Effect of active retinyl derivatives on granuloma formation

K. H. Lee, Theodore G. Tong

Research output: Contribution to journalArticle

44 Scopus citations


The naturally occurring retinyl derivatives that promote wound healing as measured by their effects on tensile strength of healing wounds also stimulate granuloma formation induced by cotton pellets. The hexosamine and hydroxyproline contents in the granuloma affected by retinyl derivatives are also increased. The mechanisms of action of retinyl derivation on wound healing are discussed.

Original languageEnglish (US)
Pages (from-to)1195-1197
Number of pages3
JournalJournal of pharmaceutical sciences
Issue number8
StatePublished - Aug 1970
Externally publishedYes



  • Granuloma formation—retinyl derivatives, effects
  • Retinyl compounds—effect on granuloma formation
  • Wound healing—mechanism of action, retinyl derivatives

ASJC Scopus subject areas

  • Pharmaceutical Science

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