Mechanism of action of salicylates VIII: Effect of topical application of retinoic acid on wound‐healing retardation action of a few anti‐inflammatory agents

K. H. Lee, Theodore G. Tong

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Oral administration of phenylbutazone, oxyphen‐butazone, mefenamic acid, flufenamic acid, or indomethacin, like salicylates or corticosteroids, retards skin wound healing in rats. The healing inhibitory action of any one of these anti‐inflammatory agents can be reversed by local application of retinoic acid.

Original languageEnglish (US)
Pages (from-to)1036-1038
Number of pages3
JournalJournal of pharmaceutical sciences
Volume59
Issue number7
DOIs
StatePublished - Jul 1970
Externally publishedYes

Keywords

  • Anti‐inflammatory agents, wound‐healing retardation—retinoic acid inhibition
  • Retinoic acid, topical application—inhibition of wound‐healing retardation of anti‐inflammatory agents
  • Salicylates, wound‐healing mechanism—analogy to other anti‐inflammatory agents

ASJC Scopus subject areas

  • Pharmaceutical Science

Fingerprint Dive into the research topics of 'Mechanism of action of salicylates VIII: Effect of topical application of retinoic acid on wound‐healing retardation action of a few anti‐inflammatory agents'. Together they form a unique fingerprint.

  • Cite this