Oral administration of phenylbutazone, oxyphen‐butazone, mefenamic acid, flufenamic acid, or indomethacin, like salicylates or corticosteroids, retards skin wound healing in rats. The healing inhibitory action of any one of these anti‐inflammatory agents can be reversed by local application of retinoic acid.
- Anti‐inflammatory agents, wound‐healing retardation—retinoic acid inhibition
- Retinoic acid, topical application—inhibition of wound‐healing retardation of anti‐inflammatory agents
- Salicylates, wound‐healing mechanism—analogy to other anti‐inflammatory agents
ASJC Scopus subject areas
- Pharmaceutical Science