A large number of stimuli are capable of triggering asthmatic attacks through mechanisms that do not involve immune pathways. Possible mechanisms involved in increased airway hyperreactivity after exposure to irritant gases, viral infections, exercise, and nonsteroidal anti-inflammatory drugs are presented. Data are reviewed suggesting that alterations in neurogenic control of airways and in airway inflammation appear to be involved in the development of airway hyperreactivity independent of the stimulus.
|Original language||English (US)|
|Number of pages||21|
|Journal||Immunology and Allergy Clinics of North America|
|State||Published - Jan 1 1992|
ASJC Scopus subject areas
- Immunology and Allergy