Mechanisms underlying thrombocytopenia in the neonatal intensive care unit

M. C. Sola, Lisa M Rimsza

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Thrombocytopenia is one of the most common hematological problems among neonates in the neonatal intensive care unit (NICU), but in the majority of cases the kinetic mechanism responsible is unclear. This review focuses on both traditional and innovative methods used to evaluate the mechanisms responsible for thrombocytopenia in neonates, and analyzes the data generated from those methods. Conclusion: Results of studies using new methods for evaluating thrombocytopenia, coupled with recent descriptions of marrow megakaryocyte mass, suggest that decreased platelet production complicates most cases of thrombocytopenia among neonates in the NICU.

Original languageEnglish (US)
Pages (from-to)66-73
Number of pages8
JournalActa Paediatrica, International Journal of Paediatrics, Supplement
Volume91
Issue number438
StatePublished - 2002
Externally publishedYes

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Neonatal Intensive Care Units
Thrombocytopenia
Megakaryocytes
Blood Platelets
Bone Marrow

Keywords

  • Bone marrow
  • Megakaryocyte progenitors
  • Megakaryocytes
  • Neonatal thrombocytopenia
  • Platelet kinetics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Mechanisms underlying thrombocytopenia in the neonatal intensive care unit. / Sola, M. C.; Rimsza, Lisa M.

In: Acta Paediatrica, International Journal of Paediatrics, Supplement, Vol. 91, No. 438, 2002, p. 66-73.

Research output: Contribution to journalArticle

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