Two mechanisms have been previously proposed for the aromatization of cyclic p-quinonemethides to indoles. A novel synthetic route to indoles via an unstable cyclic p-quinonemethide has provided additional insight into the mechanism of cyclization. Since this key intermediate lacks the functional groups required for one of the mechanistic pathways (Pathway B), it appears that cyclization occurs via Pathway A.
|Original language||English (US)|
|Number of pages||5|
|State||Published - Jan 1 1999|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry