Membranes from polymerizable lipids

Han Zhang, James R. Joubert, S. Scott Saavedra

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Scopus citations

Abstract

Potential technological applications for artificial lipid and proteo-lipid membranes, such as capsules for controlled delivery of drugs and coatings for biosensors and biomaterials, are in many cases limited by the inherent instability of lipid lamellar phases. Development of methods to stabilize artificial lipid membranes has therefore been a focus of research efforts since the 1970s. Linear and cross-linking polymerization of synthetic lipid monomers is a well-studied strategy. Several comprehensive reviews on polymerizable lipids and supramolecular structures derived from them appeared between 1985 and 2002. Consequently, this review focuses on significant developments in this field during 2000-2008. These include synthesis of new types of polymerizable lipids, creation and characterization of novel poly(lipid) membrane systems, and applications of polymerized vesicles and membranes in chemical sensing, separations science, drug delivery, materials biocompatibility, and energy storage. Polymerization of membranes to achieve stability and their functionalization for technological applications are emphasized.

Original languageEnglish (US)
Title of host publicationPolymer Membranes/Biomembranes
EditorsWolfgang meier, Wolfgang Knoll
Pages1-42
Number of pages42
Edition1
DOIs
StatePublished - Aug 30 2010

Publication series

NameAdvances in Polymer Science
Number1
Volume224
ISSN (Print)0065-3195

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Keywords

  • Lipid bilayer
  • Lipo-polymer
  • Liposome
  • Planar lipid membrane
  • Poly(lipid)
  • Polymerizable lipid
  • Stabilized membrane

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Organic Chemistry
  • Polymers and Plastics

Cite this

Zhang, H., Joubert, J. R., & Saavedra, S. S. (2010). Membranes from polymerizable lipids. In W. meier, & W. Knoll (Eds.), Polymer Membranes/Biomembranes (1 ed., pp. 1-42). (Advances in Polymer Science; Vol. 224, No. 1). https://doi.org/10.1007/12-2009-3