Memory for verbal information in individuals with HIV-associated dementia complex

Desirée A. White, Michael J. Taylor, Carol Mack, David P. Salmon, Guerry Peavy, Lee Ryan, Robert K. Heaton, J. Hampton Atkinson, James L. Chandler, Igor Grant, Mark Kelly, Mark R. Wallace, J. Allen McCutchan, Stephen A. Spector, Leon Thal, John Hesselink, Terry Jernigan, Eliezer Masliah, Clayton A. Wiley, Ian AbramsonNelson Butters, Rene Dupont, Thomas Patterson, Sidney Zisook, Dilip Jeste, Hans Sieburg, James D. Weinrich

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


Patterns of memory performance were examined for 9 participants with HIV-associated dementia (HAD), 15 HIV-seropositive participants without dementia, and 15 HIV-seronegative controls. Episodic and semantic memory were assessed using the California Verbal Learning Test, the Boston Naming Test, and Verbal Fluency tests. The HAD group showed deficits in episodic memory, with relative sparing of semantic memory. In addition, results suggest a retrieval deficit in HAD rather than a deficit in retention of information. This pattern is consistent with the presence of a subcortical dementing process and supports findings from previous neuropathological, neuroimaging, and neuropsychological studies suggesting that subcortical brain dysfunction is frequently associated with HIV disease (e.g., Navia, Jordan, and Price, 1986).

Original languageEnglish (US)
Pages (from-to)357-366
Number of pages10
JournalJournal of Clinical and Experimental Neuropsychology
Issue number3
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Psychology
  • Neurology
  • Clinical Neurology


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