Metabolic acceleration and the evolution of human brain size and life history

Herman Pontzer, Mary H. Brown, David A Raichlen, Holly Dunsworth, Brian Hare, Kara Walker, Amy Luke, Lara R. Dugas, Ramon Durazo-Arvizu, Dale Schoeller, Jacob Plange-Rhule, Pascal Bovet, Terrence E. Forrester, Estelle V. Lambert, Melissa Emery Thompson, Robert W. Shumaker, Stephen R. Ross

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Humans are distinguished from the other living apes in having larger brains and an unusual life history that combines high reproductive output with slow childhood growth and exceptional longevity. This suite of derived traits suggests major changes in energy expenditure and allocation in the human lineage, but direct measures of human and ape metabolism are needed to compare evolved energy strategies among hominoids. Here we used doubly labelled water measurements of total energy expenditure (TEE; kcal day â '1) in humans, chimpanzees, bonobos, gorillas and orangutans to test the hypothesis that the human lineage has experienced an acceleration in metabolic rate, providing energy for larger brains and faster reproduction without sacrificing maintenance and longevity. In multivariate regressions including body size and physical activity, human TEE exceeded that of chimpanzees and bonobos, gorillas and orangutans by approximately 400, 635 and 820 kcal day â '1, respectively, readily accommodating the cost of humansâ € greater brain size and reproductive output. Much of the increase in TEE is attributable to humansâ € greater basal metabolic rate (kcal day â '1), indicating increased organ metabolic activity. Humans also had the greatest body fat percentage. An increased metabolic rate, along with changes in energy allocation, was crucial in the evolution of human brain size and life history.

Original languageEnglish (US)
Pages (from-to)390-392
Number of pages3
JournalNature
Volume533
DOIs
StatePublished - May 4 2016

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Brain
Pan paniscus
Pongo
Gorilla gorilla
Pan troglodytes
Hominidae
Energy Metabolism
Basal Metabolism
Body Size
Reproduction
Adipose Tissue
Maintenance
Costs and Cost Analysis
Water
Growth

ASJC Scopus subject areas

  • General

Cite this

Pontzer, H., Brown, M. H., Raichlen, D. A., Dunsworth, H., Hare, B., Walker, K., ... Ross, S. R. (2016). Metabolic acceleration and the evolution of human brain size and life history. Nature, 533, 390-392. https://doi.org/10.1038/nature17654

Metabolic acceleration and the evolution of human brain size and life history. / Pontzer, Herman; Brown, Mary H.; Raichlen, David A; Dunsworth, Holly; Hare, Brian; Walker, Kara; Luke, Amy; Dugas, Lara R.; Durazo-Arvizu, Ramon; Schoeller, Dale; Plange-Rhule, Jacob; Bovet, Pascal; Forrester, Terrence E.; Lambert, Estelle V.; Thompson, Melissa Emery; Shumaker, Robert W.; Ross, Stephen R.

In: Nature, Vol. 533, 04.05.2016, p. 390-392.

Research output: Contribution to journalArticle

Pontzer, H, Brown, MH, Raichlen, DA, Dunsworth, H, Hare, B, Walker, K, Luke, A, Dugas, LR, Durazo-Arvizu, R, Schoeller, D, Plange-Rhule, J, Bovet, P, Forrester, TE, Lambert, EV, Thompson, ME, Shumaker, RW & Ross, SR 2016, 'Metabolic acceleration and the evolution of human brain size and life history', Nature, vol. 533, pp. 390-392. https://doi.org/10.1038/nature17654
Pontzer, Herman ; Brown, Mary H. ; Raichlen, David A ; Dunsworth, Holly ; Hare, Brian ; Walker, Kara ; Luke, Amy ; Dugas, Lara R. ; Durazo-Arvizu, Ramon ; Schoeller, Dale ; Plange-Rhule, Jacob ; Bovet, Pascal ; Forrester, Terrence E. ; Lambert, Estelle V. ; Thompson, Melissa Emery ; Shumaker, Robert W. ; Ross, Stephen R. / Metabolic acceleration and the evolution of human brain size and life history. In: Nature. 2016 ; Vol. 533. pp. 390-392.
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