Rabbits were given intraperitoneal doses of 10 or 15 mg/kg [ 14C]hexachlorophene. About 48-52% of the administered radioactivity was excreted in the feces and 21-25% in the urine over a 3.5-4-day period. Unchanged hexachlorophene (HCP) was a major constituent of feces (78%) and urine (29%) of rabbits receiving a 15 mg/kg dose of [14C]HCP. The major urinary metabolite (56%), HCP glucuronide, was isolated and characterized.
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)