Metabolism of limonene-1,2-epoxide in the rat

J. W. Regan, M. M. Morris, B. Nao, L. F. Bjeldanes

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Abstract

1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, mentha-2,8-dien-1-α and -ol and mentha-1,8-dien-6-α and -ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.

Original languageEnglish (US)
Pages (from-to)859-861
Number of pages3
JournalXenobiotica
Volume10
Issue number12
DOIs
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Biochemistry
  • Toxicology
  • Pharmacology
  • Health, Toxicology and Mutagenesis

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    Regan, J. W., Morris, M. M., Nao, B., & Bjeldanes, L. F. (1980). Metabolism of limonene-1,2-epoxide in the rat. Xenobiotica, 10(12), 859-861. https://doi.org/10.3109/00498258009033819