Metabolism of limonene-1,2-epoxide in the rat

John W Regan, M. M. Morris, B. Nao, L. F. Bjeldanes

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, mentha-2,8-dien-1-α and -ol and mentha-1,8-dien-6-α and -ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.

Original languageEnglish (US)
Pages (from-to)859-861
Number of pages3
JournalXenobiotica
Volume10
Issue number12
DOIs
StatePublished - 1980
Externally publishedYes

Fingerprint

Metabolism
Mentha
Rats
Metabolites
Glycols
Intraperitoneal Injections
Liver
limonene-1,2-epoxide
limonene

ASJC Scopus subject areas

  • Pharmacology
  • Toxicology
  • Biochemistry
  • Health, Toxicology and Mutagenesis
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Regan, J. W., Morris, M. M., Nao, B., & Bjeldanes, L. F. (1980). Metabolism of limonene-1,2-epoxide in the rat. Xenobiotica, 10(12), 859-861. https://doi.org/10.3109/00498258009033819

Metabolism of limonene-1,2-epoxide in the rat. / Regan, John W; Morris, M. M.; Nao, B.; Bjeldanes, L. F.

In: Xenobiotica, Vol. 10, No. 12, 1980, p. 859-861.

Research output: Contribution to journalArticle

Regan, JW, Morris, MM, Nao, B & Bjeldanes, LF 1980, 'Metabolism of limonene-1,2-epoxide in the rat', Xenobiotica, vol. 10, no. 12, pp. 859-861. https://doi.org/10.3109/00498258009033819
Regan, John W ; Morris, M. M. ; Nao, B. ; Bjeldanes, L. F. / Metabolism of limonene-1,2-epoxide in the rat. In: Xenobiotica. 1980 ; Vol. 10, No. 12. pp. 859-861.
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