Metabolism of tyramine in the central nervous system of the moth Manduca sexta

Gerald D. Maxwell, Marcia M. Moore, John G. Hildebrand

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Three distinct metabolites of tyramine are produced by central nervous tissue of pharate-adult Manduca sexta incubated in vitro with [3H]-tyramine. The chemical identities of these metabolites have been sought by a combination of electrophoretic, chromatographic, hydrolytic and enzymic procedures. One of the compounds is N-acetyltyramine, and the others appear to be β-alanyltyramine and a sugar conjugate, possibly of N-acetyltyramine.

Original languageEnglish (US)
Pages (from-to)657-665
Number of pages9
JournalInsect Biochemistry
Volume10
Issue number6
DOIs
StatePublished - 1980
Externally publishedYes

Keywords

  • Manduca sexta
  • N-acetyltyramine
  • Tyramine
  • biogenic amines
  • monoamine metabolism
  • nervous system
  • β-alanyltyramine

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