Method of calibrating response statistics for ML estimation of 3D interaction position in a thick-detector gamma camera

William C.J. Hunter, Harrison H. Barrett, Lars R. Furenlid, Stephen K. Moore

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

High-energy photon detectors are often made thick in order to improve their photon-detection efficiency. To avoid issues of parallax and increased signal variance that result from random interaction depth, we must determine the 3D interaction position in the imaging detector. With this goal in mind, we examine a method of calibrating response statistics of a thick-detector gamma camera to produce a maximum- likelihood estimate of 3D interaction position. We parameterize the mean detector response as a function of 3D position and estimate the parameters by maximizing their likelihood given prior knowledge of the pathlength distribution and a complete list of camera signals for an ensemble of gamma-ray interactions. Demonstrating this calibration method with simulated gamma-camera data, we show that the resulting calibration is accurate and can be used to produce unbiased estimates of 3D interaction position.

Original languageEnglish (US)
Title of host publication2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Pages4359-4363
Number of pages5
DOIs
StatePublished - Dec 1 2007
Event2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC - Honolulu, HI, United States
Duration: Oct 27 2007Nov 3 2007

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume6
ISSN (Print)1095-7863

Other

Other2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
CountryUnited States
CityHonolulu, HI
Period10/27/0711/3/07

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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    Hunter, W. C. J., Barrett, H. H., Furenlid, L. R., & Moore, S. K. (2007). Method of calibrating response statistics for ML estimation of 3D interaction position in a thick-detector gamma camera. In 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC (pp. 4359-4363). [4437079] (IEEE Nuclear Science Symposium Conference Record; Vol. 6). https://doi.org/10.1109/NSSMIC.2007.4437079