Methyl diethyldithiocarbamate, a metabolite of disulfiram in man

John Cobby, Michael Mayersohn, Sathi Selliah

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Following the oral administration of disulfiram to alcoholic patient volunteers, methyl diethyldithiocarbamate (MeDDC) was noted in blood withdrawn between one and two hours after dosing. This is consistent with previous reports of MeDDC in mice and dogs. It is suggested that MeDDC is an intermediate in the formation of urinary sulfate.

Original languageEnglish (US)
Pages (from-to)937-941
Number of pages5
JournalLife Sciences
Volume21
Issue number7
DOIs
StatePublished - Oct 1 1977

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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