Microendoscopes for imaging of the pancreas

Angelique Kano, Andrew R. Rouse, Shona M. Kroto, Arthur F. Gmitro

Research output: Contribution to journalConference article

1 Scopus citations

Abstract

Patients diagnosed with pancreatic cancer have a 5-year survival rate of only 3%. Endoscopic imaging of the pancreas is limited by the small size of the pancreatic duct, which has an average size of 3 mm. To improve imaging capabilities for the pancreatic duct, two small catheter-based imaging systems have been developed that will fit through the therapeutic channel of a clinical endoscope and into the pancreatic duct. One is a miniature endoscope designed to provide macro-imaging of tissue with both white light reflectance and fluorescence imaging modes. The 1.75 mm diameter catheter consists of separate illumination and imaging channels. At a nominal focal distance of 10 mm, the field of view of the system is ∼ 10 mm, and the corresponding in-plane resolution is 60 μm. To complement the broadfield view of the tissue, a confocal microendoscope with 2 μm lateral resolution over a field of view of 450 μm and 25 μm axial resolution has been developed. With an outer diameter of 3 mm, the catheter in this system will also fit through the therapeutic channel and into the pancreatic duct. Images of tissue with both the miniature endoscope and confocal microendoscope are presented.

Original languageEnglish (US)
Pages (from-to)50-58
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5318
DOIs
StatePublished - Oct 27 2004
EventProgress in Biomedical Optics and Imaging - Adavnced Biomedical and Clinical Diagnostic Systems II - San Jose, CA, United States
Duration: Jan 25 2004Jan 26 2004

Keywords

  • Broadfield
  • Cancer
  • Confocal
  • Fluorescence
  • Microscopic
  • Pancreas
  • White-light reflectance

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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