Microwave-induced thermoacoustic imaging model for potential breast cancer detection

Xiong Wang, Daniel R. Bauer, Russell S Witte, Hao Xin

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

In this study, we develop a complete microwave-induced thermoacoustic imaging (TAI) model for potential breast cancer imaging application. Acoustic pressures generated by different breast tissue targets are investigated by finite-difference time-domain simulations of the entire TAI process including the feeding antenna, matching mechanism, fluidic environment, 3-D breast model, and acoustic transducer. Simulation results achieve quantitative relationships between the input microwave peak power and the resulting specific absorption rate as well as the output acoustic pressure. Microwave frequency dependence of the acoustic signals due to different breast tissues is established across a broadband frequency range (2.3-12GHz), suggesting key advantages of spectroscopic TAI compare to TAI at a single frequency. Reconstructed thermoacoustic images are consistent with the modeling results. This model will contribute to design, optimization, and safety evaluation of microwave-induced TAI and spectroscopy.

Original languageEnglish (US)
Article number14
Pages (from-to)2782-2791
Number of pages10
JournalIEEE Transactions on Biomedical Engineering
Volume59
Issue number10
DOIs
StatePublished - 2012

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Thermoacoustics
Microwaves
Imaging techniques
Acoustics
Tissue
Acoustic transducers
Microwave frequencies
Fluidics
Spectroscopy
Antennas

Keywords

  • Breast cancer detection
  • microwave spectroscopy
  • safety evaluation
  • thermoacoustic imaging (TAI)

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Microwave-induced thermoacoustic imaging model for potential breast cancer detection. / Wang, Xiong; Bauer, Daniel R.; Witte, Russell S; Xin, Hao.

In: IEEE Transactions on Biomedical Engineering, Vol. 59, No. 10, 14, 2012, p. 2782-2791.

Research output: Contribution to journalArticle

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