Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate

Casey A. Kernag, James M. Bobbitt, Dominic V Mcgrath

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Hydroxymethyl substituted aromatic heterocycles, including pyridines, furans, and thiophenes, are oxidized to the corresponding aldehydes in excellent yields by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1- oxoammonium perchlorate (1) with minimal workup.

Original languageEnglish (US)
Pages (from-to)1635-1636
Number of pages2
JournalTetrahedron Letters
Volume40
Issue number9
DOIs
StatePublished - Feb 26 1999

Fingerprint

Furans
Pyridines
Thiophenes
Aldehydes
Alcohols
Oxidation
2,2,6,6-tetramethylpiperidide
perchlorate

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate. / Kernag, Casey A.; Bobbitt, James M.; Mcgrath, Dominic V.

In: Tetrahedron Letters, Vol. 40, No. 9, 26.02.1999, p. 1635-1636.

Research output: Contribution to journalArticle

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