Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate

Casey A. Kernag, James M. Bobbitt, Dominic V. McGrath

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Hydroxymethyl substituted aromatic heterocycles, including pyridines, furans, and thiophenes, are oxidized to the corresponding aldehydes in excellent yields by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1- oxoammonium perchlorate (1) with minimal workup.

Original languageEnglish (US)
Pages (from-to)1635-1636
Number of pages2
JournalTetrahedron Letters
Volume40
Issue number9
DOIs
StatePublished - Feb 26 1999

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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