Minimum information about an uncultivated virus genome (MIUVIG)

Simon Roux; Evelien M. Adriaenssens; Bas E. Dutilh; Eugene V. Koonin; Andrew M. Kropinski; Mart Krupovic; Jens H. Kuhn; Rob Lavigne; J. Rodney Brister; Arvind Varsani; Clara Amid; Ramy K. Aziz; Seth R. Bordenstein; Peer Bork; Mya Breitbart; Guy R. Cochrane; Rebecca A. Daly; Christelle Desnues; Melissa B. Duhaime; Joanne B. Emerson; François Enault; Jed A. Fuhrman; Pascal Hingamp; Philip Hugenholtz; Bonnie L. Hurwitz; Natalia N. Ivanova; Jessica M. Labonté; Kyung Bum Lee; Rex R. Malmstrom; Manuel Martinez-Garcia; Ilene Karsch Mizrachi; Hiroyuki Ogata; David Páez-Espino; Marie Agnès Petit; Catherine Putonti; Thomas Rattei; Alejandro Reyes; Francisco Rodriguez-Valera; Karyna Rosario; Lynn Schriml; Frederik Schulz; Grieg F. Steward; Matthew B. Sullivan; Shinichi Sunagawa; Curtis A. Suttle; Ben Temperton; Susannah G. Tringe; Rebecca Vega Thurber; Nicole S. Webster; Katrine L. Whiteson; Steven W. Wilhelm; K. Eric Wommack; Tanja Woyke; Kelly C. Wrighton; Pelin Yilmaz; Takashi Yoshida; Mark J. Young; Natalya Yutin; Lisa Zeigler Allen; Nikos C. Kyrpides; Emiley A. Eloe-Fadrosh

doi:10.1038/nbt.4306

Minimum information about an uncultivated virus genome (MIUVIG)

Simon Roux, Evelien M. Adriaenssens, Bas E. Dutilh, Eugene V. Koonin, Andrew M. Kropinski, Mart Krupovic, Jens H. Kuhn, Rob Lavigne, J. Rodney Brister, Arvind Varsani, Clara Amid, Ramy K. Aziz, Seth R. Bordenstein, Peer Bork, Mya Breitbart, Guy R. Cochrane, Rebecca A. Daly, Christelle Desnues, Melissa B. Duhaime, Joanne B. EmersonFrançois Enault, Jed A. Fuhrman, Pascal Hingamp, Philip Hugenholtz, Bonnie L. Hurwitz, Natalia N. Ivanova, Jessica M. Labonté, Kyung Bum Lee, Rex R. Malmstrom, Manuel Martinez-Garcia, Ilene Karsch Mizrachi, Hiroyuki Ogata, David Páez-Espino, Marie Agnès Petit, Catherine Putonti, Thomas Rattei, Alejandro Reyes, Francisco Rodriguez-Valera, Karyna Rosario, Lynn Schriml, Frederik Schulz, Grieg F. Steward, Matthew B. Sullivan, Shinichi Sunagawa, Curtis A. Suttle, Ben Temperton, Susannah G. Tringe, Rebecca Vega Thurber, Nicole S. Webster, Katrine L. Whiteson, Steven W. Wilhelm, K. Eric Wommack, Tanja Woyke, Kelly C. Wrighton, Pelin Yilmaz, Takashi Yoshida, Mark J. Young, Natalya Yutin, Lisa Zeigler Allen, Nikos C. Kyrpides, Emiley A. Eloe-Fadrosh

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Abstract

We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard for reporting sequences of uncultivated virus genomes. Minimum Information about an Uncultivated Virus Genome (MIUViG) standards were developed within the Genomic Standards Consortium framework and include virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction. Community-wide adoption of MIUViG standards, which complement the Minimum Information about a Single Amplified Genome (MISAG) and Metagenome-Assembled Genome (MIMAG) standards for uncultivated bacteria and archaea, will improve the reporting of uncultivated virus genomes in public databases. In turn, this should enable more robust comparative studies and a systematic exploration of the global virosphere.

Original language	English (US)
Pages (from-to)	29-37
Number of pages	9
Journal	Nature biotechnology
Volume	37
Issue number	1
DOIs	https://doi.org/10.1038/nbt.4306
State	Published - Jan 1 2019

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology
Molecular Medicine
Biomedical Engineering

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Roux, S., Adriaenssens, E. M., Dutilh, B. E., Koonin, E. V., Kropinski, A. M., Krupovic, M., Kuhn, J. H., Lavigne, R., Brister, J. R., Varsani, A., Amid, C., Aziz, R. K., Bordenstein, S. R., Bork, P., Breitbart, M., Cochrane, G. R., Daly, R. A., Desnues, C., Duhaime, M. B., ... Eloe-Fadrosh, E. A. (2019). Minimum information about an uncultivated virus genome (MIUVIG). Nature biotechnology, 37(1), 29-37. https://doi.org/10.1038/nbt.4306

Minimum information about an uncultivated virus genome (MIUVIG). / Roux, Simon; Adriaenssens, Evelien M.; Dutilh, Bas E.; Koonin, Eugene V.; Kropinski, Andrew M.; Krupovic, Mart; Kuhn, Jens H.; Lavigne, Rob; Brister, J. Rodney; Varsani, Arvind; Amid, Clara; Aziz, Ramy K.; Bordenstein, Seth R.; Bork, Peer; Breitbart, Mya; Cochrane, Guy R.; Daly, Rebecca A.; Desnues, Christelle; Duhaime, Melissa B.; Emerson, Joanne B.; Enault, François; Fuhrman, Jed A.; Hingamp, Pascal; Hugenholtz, Philip; Hurwitz, Bonnie L.; Ivanova, Natalia N.; Labonté, Jessica M.; Lee, Kyung Bum; Malmstrom, Rex R.; Martinez-Garcia, Manuel; Mizrachi, Ilene Karsch; Ogata, Hiroyuki; Páez-Espino, David; Petit, Marie Agnès; Putonti, Catherine; Rattei, Thomas; Reyes, Alejandro; Rodriguez-Valera, Francisco; Rosario, Karyna; Schriml, Lynn; Schulz, Frederik; Steward, Grieg F.; Sullivan, Matthew B.; Sunagawa, Shinichi; Suttle, Curtis A.; Temperton, Ben; Tringe, Susannah G.; Thurber, Rebecca Vega; Webster, Nicole S.; Whiteson, Katrine L.; Wilhelm, Steven W.; Wommack, K. Eric; Woyke, Tanja; Wrighton, Kelly C.; Yilmaz, Pelin; Yoshida, Takashi; Young, Mark J.; Yutin, Natalya; Allen, Lisa Zeigler; Kyrpides, Nikos C.; Eloe-Fadrosh, Emiley A.

In: Nature biotechnology, Vol. 37, No. 1, 01.01.2019, p. 29-37.

Research output: Contribution to journal › Article › peer-review

Roux, S, Adriaenssens, EM, Dutilh, BE, Koonin, EV, Kropinski, AM, Krupovic, M, Kuhn, JH, Lavigne, R, Brister, JR, Varsani, A, Amid, C, Aziz, RK, Bordenstein, SR, Bork, P, Breitbart, M, Cochrane, GR, Daly, RA, Desnues, C, Duhaime, MB, Emerson, JB, Enault, F, Fuhrman, JA, Hingamp, P, Hugenholtz, P, Hurwitz, BL, Ivanova, NN, Labonté, JM, Lee, KB, Malmstrom, RR, Martinez-Garcia, M, Mizrachi, IK, Ogata, H, Páez-Espino, D, Petit, MA, Putonti, C, Rattei, T, Reyes, A, Rodriguez-Valera, F, Rosario, K, Schriml, L, Schulz, F, Steward, GF, Sullivan, MB, Sunagawa, S, Suttle, CA, Temperton, B, Tringe, SG, Thurber, RV, Webster, NS, Whiteson, KL, Wilhelm, SW, Wommack, KE, Woyke, T, Wrighton, KC, Yilmaz, P, Yoshida, T, Young, MJ, Yutin, N, Allen, LZ, Kyrpides, NC & Eloe-Fadrosh, EA 2019, 'Minimum information about an uncultivated virus genome (MIUVIG)', Nature biotechnology, vol. 37, no. 1, pp. 29-37. https://doi.org/10.1038/nbt.4306

Roux, Simon ; Adriaenssens, Evelien M. ; Dutilh, Bas E. ; Koonin, Eugene V. ; Kropinski, Andrew M. ; Krupovic, Mart ; Kuhn, Jens H. ; Lavigne, Rob ; Brister, J. Rodney ; Varsani, Arvind ; Amid, Clara ; Aziz, Ramy K. ; Bordenstein, Seth R. ; Bork, Peer ; Breitbart, Mya ; Cochrane, Guy R. ; Daly, Rebecca A. ; Desnues, Christelle ; Duhaime, Melissa B. ; Emerson, Joanne B. ; Enault, François ; Fuhrman, Jed A. ; Hingamp, Pascal ; Hugenholtz, Philip ; Hurwitz, Bonnie L. ; Ivanova, Natalia N. ; Labonté, Jessica M. ; Lee, Kyung Bum ; Malmstrom, Rex R. ; Martinez-Garcia, Manuel ; Mizrachi, Ilene Karsch ; Ogata, Hiroyuki ; Páez-Espino, David ; Petit, Marie Agnès ; Putonti, Catherine ; Rattei, Thomas ; Reyes, Alejandro ; Rodriguez-Valera, Francisco ; Rosario, Karyna ; Schriml, Lynn ; Schulz, Frederik ; Steward, Grieg F. ; Sullivan, Matthew B. ; Sunagawa, Shinichi ; Suttle, Curtis A. ; Temperton, Ben ; Tringe, Susannah G. ; Thurber, Rebecca Vega ; Webster, Nicole S. ; Whiteson, Katrine L. ; Wilhelm, Steven W. ; Wommack, K. Eric ; Woyke, Tanja ; Wrighton, Kelly C. ; Yilmaz, Pelin ; Yoshida, Takashi ; Young, Mark J. ; Yutin, Natalya ; Allen, Lisa Zeigler ; Kyrpides, Nikos C. ; Eloe-Fadrosh, Emiley A. / Minimum information about an uncultivated virus genome (MIUVIG). In: Nature biotechnology. 2019 ; Vol. 37, No. 1. pp. 29-37.

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title = "Minimum information about an uncultivated virus genome (MIUVIG)",

abstract = "We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard for reporting sequences of uncultivated virus genomes. Minimum Information about an Uncultivated Virus Genome (MIUViG) standards were developed within the Genomic Standards Consortium framework and include virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction. Community-wide adoption of MIUViG standards, which complement the Minimum Information about a Single Amplified Genome (MISAG) and Metagenome-Assembled Genome (MIMAG) standards for uncultivated bacteria and archaea, will improve the reporting of uncultivated virus genomes in public databases. In turn, this should enable more robust comparative studies and a systematic exploration of the global virosphere.",

author = "Simon Roux and Adriaenssens, {Evelien M.} and Dutilh, {Bas E.} and Koonin, {Eugene V.} and Kropinski, {Andrew M.} and Mart Krupovic and Kuhn, {Jens H.} and Rob Lavigne and Brister, {J. Rodney} and Arvind Varsani and Clara Amid and Aziz, {Ramy K.} and Bordenstein, {Seth R.} and Peer Bork and Mya Breitbart and Cochrane, {Guy R.} and Daly, {Rebecca A.} and Christelle Desnues and Duhaime, {Melissa B.} and Emerson, {Joanne B.} and Fran{\c c}ois Enault and Fuhrman, {Jed A.} and Pascal Hingamp and Philip Hugenholtz and Hurwitz, {Bonnie L.} and Ivanova, {Natalia N.} and Labont{\'e}, {Jessica M.} and Lee, {Kyung Bum} and Malmstrom, {Rex R.} and Manuel Martinez-Garcia and Mizrachi, {Ilene Karsch} and Hiroyuki Ogata and David P{\'a}ez-Espino and Petit, {Marie Agn{\`e}s} and Catherine Putonti and Thomas Rattei and Alejandro Reyes and Francisco Rodriguez-Valera and Karyna Rosario and Lynn Schriml and Frederik Schulz and Steward, {Grieg F.} and Sullivan, {Matthew B.} and Shinichi Sunagawa and Suttle, {Curtis A.} and Ben Temperton and Tringe, {Susannah G.} and Thurber, {Rebecca Vega} and Webster, {Nicole S.} and Whiteson, {Katrine L.} and Wilhelm, {Steven W.} and Wommack, {K. Eric} and Tanja Woyke and Wrighton, {Kelly C.} and Pelin Yilmaz and Takashi Yoshida and Young, {Mark J.} and Natalya Yutin and Allen, {Lisa Zeigler} and Kyrpides, {Nikos C.} and Eloe-Fadrosh, {Emiley A.}",

note = "Funding Information: This work was supported by the Laboratory Directed Research and Development Program of Lawrence Berkeley National Laboratory under US Department of Energy Contract No. DE-AC02-05CH11231 for S.R.; the Netherlands Organization for Scientific Research (NWO) Vidi grant 864.14.004 for B.E.D.; the Intramural Research Program of the National Library of Medicine, National Institutes of Health for E.V.K., I.K.M., J.R.B. and N.Y.; the Virus-X project (EU Horizon 2020, No. 685778) for F.E. and M.K.; Battelle Memorial Institute{\textquoteright}s prime contract with the US National Institute of Allergy and Infectious Diseases (NIAID) under Contract No. HHSN272200700016I for J.H.K.; the GOA grant “Bacteriophage Biosystems” from KU Leuven for R.L.; the European Molecular Biology Laboratory for C.A. and G.R.C.; Cairo University Grant 2016-57 for R.K.A.; National Science Foundation award 1456778, National Institutes of Health awards R01 AI132581 and R21 HD086833, and The Vanderbilt Microbiome Initiative award for S.R.B.; National Science Foundation awards DEB-1239976 for M.B. and K.R. and DEB-1555854 for M.B.; the NSF Early Career award DEB-1555854 and NSF Dimensions of Biodiversity #1342701 for K.C.W. and R.A.D.; the Agence Nationale de la Recherche JCJC grant ANR-13-JSV6-0004 and Investissements d{\textquoteright}Avenir M{\'e}diterran{\'e}e Infection 10-IAHU-03 for C.D.; the Gordon and Betty Moore Foundation Marine Microbiology Initiative No. 3779 and the Simons Foundation for J.A.F.; the French government “Investissements d{\textquoteright}Avenir” program OCEANOMICS ANR-11-BTBR-0008 and European FEDER Fund 1166-39417 for P. Hingamp; Australian Research Council Laureate Fellowship FL150100038 to P. Hugenholtz the National Science Foundation award 1801367 and C-DEBI Research Grant for J.M.L.; the Gordon and Betty Moore Foundation grant 5334 and Ministry of Economy and Competitivity refs. CGL2013-40564-R and SAF2013-49267-EXP for M.M.-G.; the Grant-in-Aid for Scientific Research on Innovative Areas from the Ministry of Education, Culture, Science, Sports, and Technology (MEXT) of Japan No. 16H06429, 16K21723, and 16H06437 for H.O. and T.Y.; National Science Foundation award DBI-1661357 to C.P.; the Ministry of Economy and Competitivity ref CGL2016-76273-P (cofunded with FEDER funds) for F.R.-V.; the Gordon and Betty Moore Foundation awards 3305 and 3790 and NSF Biological Oceanography OCE 1536989 for M.B.S.; the ETH Zurich and Helmut Horten Foundation and the Novartis Foundation for Medical-Biological Research (17B077) for S.S.; a BIOS-SCOPE award from Simons Foundation International and NERC award NE/P008534/1 to B.T.; NSF Biological Oceanography Grant 1635913 for R.V.T.; the Australian Research Council Future Fellowship FT120100480 for N.S.W.; a Gilead Sciences Cystic Fibrosis Research Scholarship for K.L.W.; Gordon and Better Moore Foundation Grant 4971 for S.W.W.; the NSF EPSCoR grant 1736030 for K.E.W.; the National Science Foundation award DEB-4W4596 and National Institutes of Health award R01 GM117361 for M.J.Y.; the Gordon and Betty Moore Foundation No. 7000 and the National Oceanic and Atmospheric Administration (NOAA) under award NA15OAR4320071 for L.Z.A. DDBJ is supported by ROIS and MEXT. The work conducted by the US Department of Energy Joint Genome Institute is supported by the Office of Science of the US Department of Energy under contract no. DE-AC02-05CH11231. The views and conclusions contained in this document are those of the authors and should not be interpreted as necessarily representing the official policies, either expressed or implied, of the US Department of Health and Human Services or of the institutions and companies affiliated with the authors. B.E.D., A.K., M.K., J.H.K., R.L. and A.V. are members of the ICTV Executive Committee, but the views and opinions expressed are those of the authors and not those of the ICTV. Publisher Copyright: {\textcopyright} 2019, Nature Publishing Group. All rights reserved. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.",

year = "2019",

month = jan,

day = "1",

doi = "10.1038/nbt.4306",

language = "English (US)",

volume = "37",

pages = "29--37",

journal = "Biotechnology",

issn = "1087-0156",

publisher = "Nature Publishing Group",

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TY - JOUR

T1 - Minimum information about an uncultivated virus genome (MIUVIG)

AU - Roux, Simon

AU - Adriaenssens, Evelien M.

AU - Dutilh, Bas E.

AU - Koonin, Eugene V.

AU - Kropinski, Andrew M.

AU - Krupovic, Mart

AU - Kuhn, Jens H.

AU - Lavigne, Rob

AU - Brister, J. Rodney

AU - Varsani, Arvind

AU - Amid, Clara

AU - Aziz, Ramy K.

AU - Bordenstein, Seth R.

AU - Bork, Peer

AU - Breitbart, Mya

AU - Cochrane, Guy R.

AU - Daly, Rebecca A.

AU - Desnues, Christelle

AU - Duhaime, Melissa B.

AU - Emerson, Joanne B.

AU - Enault, François

AU - Fuhrman, Jed A.

AU - Hingamp, Pascal

AU - Hugenholtz, Philip

AU - Hurwitz, Bonnie L.

AU - Ivanova, Natalia N.

AU - Labonté, Jessica M.

AU - Lee, Kyung Bum

AU - Malmstrom, Rex R.

AU - Martinez-Garcia, Manuel

AU - Mizrachi, Ilene Karsch

AU - Ogata, Hiroyuki

AU - Páez-Espino, David

AU - Petit, Marie Agnès

AU - Putonti, Catherine

AU - Rattei, Thomas

AU - Reyes, Alejandro

AU - Rodriguez-Valera, Francisco

AU - Rosario, Karyna

AU - Schriml, Lynn

AU - Schulz, Frederik

AU - Steward, Grieg F.

AU - Sullivan, Matthew B.

AU - Sunagawa, Shinichi

AU - Suttle, Curtis A.

AU - Temperton, Ben

AU - Tringe, Susannah G.

AU - Thurber, Rebecca Vega

AU - Webster, Nicole S.

AU - Whiteson, Katrine L.

AU - Wilhelm, Steven W.

AU - Wommack, K. Eric

AU - Woyke, Tanja

AU - Wrighton, Kelly C.

AU - Yilmaz, Pelin

AU - Yoshida, Takashi

AU - Young, Mark J.

AU - Yutin, Natalya

AU - Allen, Lisa Zeigler

AU - Kyrpides, Nikos C.

AU - Eloe-Fadrosh, Emiley A.

N1 - Funding Information: This work was supported by the Laboratory Directed Research and Development Program of Lawrence Berkeley National Laboratory under US Department of Energy Contract No. DE-AC02-05CH11231 for S.R.; the Netherlands Organization for Scientific Research (NWO) Vidi grant 864.14.004 for B.E.D.; the Intramural Research Program of the National Library of Medicine, National Institutes of Health for E.V.K., I.K.M., J.R.B. and N.Y.; the Virus-X project (EU Horizon 2020, No. 685778) for F.E. and M.K.; Battelle Memorial Institute’s prime contract with the US National Institute of Allergy and Infectious Diseases (NIAID) under Contract No. HHSN272200700016I for J.H.K.; the GOA grant “Bacteriophage Biosystems” from KU Leuven for R.L.; the European Molecular Biology Laboratory for C.A. and G.R.C.; Cairo University Grant 2016-57 for R.K.A.; National Science Foundation award 1456778, National Institutes of Health awards R01 AI132581 and R21 HD086833, and The Vanderbilt Microbiome Initiative award for S.R.B.; National Science Foundation awards DEB-1239976 for M.B. and K.R. and DEB-1555854 for M.B.; the NSF Early Career award DEB-1555854 and NSF Dimensions of Biodiversity #1342701 for K.C.W. and R.A.D.; the Agence Nationale de la Recherche JCJC grant ANR-13-JSV6-0004 and Investissements d’Avenir Méditerranée Infection 10-IAHU-03 for C.D.; the Gordon and Betty Moore Foundation Marine Microbiology Initiative No. 3779 and the Simons Foundation for J.A.F.; the French government “Investissements d’Avenir” program OCEANOMICS ANR-11-BTBR-0008 and European FEDER Fund 1166-39417 for P. Hingamp; Australian Research Council Laureate Fellowship FL150100038 to P. Hugenholtz the National Science Foundation award 1801367 and C-DEBI Research Grant for J.M.L.; the Gordon and Betty Moore Foundation grant 5334 and Ministry of Economy and Competitivity refs. CGL2013-40564-R and SAF2013-49267-EXP for M.M.-G.; the Grant-in-Aid for Scientific Research on Innovative Areas from the Ministry of Education, Culture, Science, Sports, and Technology (MEXT) of Japan No. 16H06429, 16K21723, and 16H06437 for H.O. and T.Y.; National Science Foundation award DBI-1661357 to C.P.; the Ministry of Economy and Competitivity ref CGL2016-76273-P (cofunded with FEDER funds) for F.R.-V.; the Gordon and Betty Moore Foundation awards 3305 and 3790 and NSF Biological Oceanography OCE 1536989 for M.B.S.; the ETH Zurich and Helmut Horten Foundation and the Novartis Foundation for Medical-Biological Research (17B077) for S.S.; a BIOS-SCOPE award from Simons Foundation International and NERC award NE/P008534/1 to B.T.; NSF Biological Oceanography Grant 1635913 for R.V.T.; the Australian Research Council Future Fellowship FT120100480 for N.S.W.; a Gilead Sciences Cystic Fibrosis Research Scholarship for K.L.W.; Gordon and Better Moore Foundation Grant 4971 for S.W.W.; the NSF EPSCoR grant 1736030 for K.E.W.; the National Science Foundation award DEB-4W4596 and National Institutes of Health award R01 GM117361 for M.J.Y.; the Gordon and Betty Moore Foundation No. 7000 and the National Oceanic and Atmospheric Administration (NOAA) under award NA15OAR4320071 for L.Z.A. DDBJ is supported by ROIS and MEXT. The work conducted by the US Department of Energy Joint Genome Institute is supported by the Office of Science of the US Department of Energy under contract no. DE-AC02-05CH11231. The views and conclusions contained in this document are those of the authors and should not be interpreted as necessarily representing the official policies, either expressed or implied, of the US Department of Health and Human Services or of the institutions and companies affiliated with the authors. B.E.D., A.K., M.K., J.H.K., R.L. and A.V. are members of the ICTV Executive Committee, but the views and opinions expressed are those of the authors and not those of the ICTV. Publisher Copyright: © 2019, Nature Publishing Group. All rights reserved. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard for reporting sequences of uncultivated virus genomes. Minimum Information about an Uncultivated Virus Genome (MIUViG) standards were developed within the Genomic Standards Consortium framework and include virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction. Community-wide adoption of MIUViG standards, which complement the Minimum Information about a Single Amplified Genome (MISAG) and Metagenome-Assembled Genome (MIMAG) standards for uncultivated bacteria and archaea, will improve the reporting of uncultivated virus genomes in public databases. In turn, this should enable more robust comparative studies and a systematic exploration of the global virosphere.

AB - We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard for reporting sequences of uncultivated virus genomes. Minimum Information about an Uncultivated Virus Genome (MIUViG) standards were developed within the Genomic Standards Consortium framework and include virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction. Community-wide adoption of MIUViG standards, which complement the Minimum Information about a Single Amplified Genome (MISAG) and Metagenome-Assembled Genome (MIMAG) standards for uncultivated bacteria and archaea, will improve the reporting of uncultivated virus genomes in public databases. In turn, this should enable more robust comparative studies and a systematic exploration of the global virosphere.

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DO - 10.1038/nbt.4306

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