Whereas the cardiorespiratory derangements of severe obesity have received careful scrutiny, the biochemical alterations unique to that state are not well known. This review will examine in morbidly obese patients the hepatic abnormalities related to morphology, function, and lipid metabolism. Altered xenobiotic biotransformation will then be discussed. Available studies in man will emphasize what is known about the biochemical aberrations exemplified by this abnormal biologic state.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Pharmacology, Toxicology and Pharmaceutics(all)