Mitochondrial Miro GTPases coordinate mitochondrial and peroxisomal dynamics

Research output: Contribution to journalReview articlepeer-review


Mitochondria and peroxisomes are highly dynamic, multifunctional organelles. Both perform key roles for cellular physiology and homoeostasis by mediating bioenergetics, biosynthesis, and/or signalling. To support cellular function, they must be properly distributed, of proper size, and be able to interact with other organelles. Accumulating evidence suggests that the small atypical GTPase Miro provides a central signalling node to coordinate mitochondrial as well as peroxisomal dynamics. In this review, I summarize our current understanding of Miro-dependent functions and molecular mechanisms underlying the proper distribution, size and function of mitochondria and peroxisomes.

Original languageEnglish (US)
JournalSmall GTPases
StateAccepted/In press - 2020


  • Miro
  • Small GTPase
  • membrane dynamics
  • mitochondria
  • mitochondrial dynamics
  • motility
  • peroxisomal dynamics
  • peroxisome

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology

Fingerprint Dive into the research topics of 'Mitochondrial Miro GTPases coordinate mitochondrial and peroxisomal dynamics'. Together they form a unique fingerprint.

Cite this