Abstract
The structure and conformational dynamic changes that occur in cytoskeletal proteins within living cells and evidence for their participation in computational processing are described. The role of cellular automata, in which lattice subunits with discrete states interact only with nearest neighbors, in molecular computing is discussed. Simple rules governing subunit neighbor interactions can lead to complex behavior capable of computation. It is shown that cellular automata may be implemented in the conformational relationships among neighboring protein subunits of cytoskeletal polymers including microtubules, and microtubule conformational automata networks may signal, adapt, recognize, and subserve neural-level learning.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 30-39 |
| Number of pages | 10 |
| Journal | Computer |
| Volume | 25 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1992 |
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ASJC Scopus subject areas
- Computer Graphics and Computer-Aided Design
- Hardware and Architecture
- Software
Cite this
Models for molecular computation : Conformational automata in the cytoskeleton. / Hameroff, Stuart R; Dayhoff, Judith E.; Lahoz-Beltra, Rafael; Samsonovich, Alexei V.; Rasmussen, Steen.
In: Computer, Vol. 25, No. 11, 11.1992, p. 30-39.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Models for molecular computation
T2 - Conformational automata in the cytoskeleton
AU - Hameroff, Stuart R
AU - Dayhoff, Judith E.
AU - Lahoz-Beltra, Rafael
AU - Samsonovich, Alexei V.
AU - Rasmussen, Steen
PY - 1992/11
Y1 - 1992/11
N2 - The structure and conformational dynamic changes that occur in cytoskeletal proteins within living cells and evidence for their participation in computational processing are described. The role of cellular automata, in which lattice subunits with discrete states interact only with nearest neighbors, in molecular computing is discussed. Simple rules governing subunit neighbor interactions can lead to complex behavior capable of computation. It is shown that cellular automata may be implemented in the conformational relationships among neighboring protein subunits of cytoskeletal polymers including microtubules, and microtubule conformational automata networks may signal, adapt, recognize, and subserve neural-level learning.
AB - The structure and conformational dynamic changes that occur in cytoskeletal proteins within living cells and evidence for their participation in computational processing are described. The role of cellular automata, in which lattice subunits with discrete states interact only with nearest neighbors, in molecular computing is discussed. Simple rules governing subunit neighbor interactions can lead to complex behavior capable of computation. It is shown that cellular automata may be implemented in the conformational relationships among neighboring protein subunits of cytoskeletal polymers including microtubules, and microtubule conformational automata networks may signal, adapt, recognize, and subserve neural-level learning.
UR - http://www.scopus.com/inward/record.url?scp=0026955252&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026955252&partnerID=8YFLogxK
U2 - 10.1109/2.166406
DO - 10.1109/2.166406
M3 - Article
AN - SCOPUS:0026955252
VL - 25
SP - 30
EP - 39
JO - ACM SIGPLAN/SIGSOFT Workshop on Program Analysis for Software Tools and Engineering
JF - ACM SIGPLAN/SIGSOFT Workshop on Program Analysis for Software Tools and Engineering
SN - 0018-9162
IS - 11
ER -