Models for molecular computation: Conformational automata in the cytoskeleton

Stuart R Hameroff, Judith E. Dayhoff, Rafael Lahoz-Beltra, Alexei V. Samsonovich, Steen Rasmussen

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The structure and conformational dynamic changes that occur in cytoskeletal proteins within living cells and evidence for their participation in computational processing are described. The role of cellular automata, in which lattice subunits with discrete states interact only with nearest neighbors, in molecular computing is discussed. Simple rules governing subunit neighbor interactions can lead to complex behavior capable of computation. It is shown that cellular automata may be implemented in the conformational relationships among neighboring protein subunits of cytoskeletal polymers including microtubules, and microtubule conformational automata networks may signal, adapt, recognize, and subserve neural-level learning.

Original languageEnglish (US)
Pages (from-to)30-39
Number of pages10
JournalComputer
Volume25
Issue number11
DOIs
StatePublished - Nov 1992

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Cellular automata
Proteins
Cells
Polymers
Processing

ASJC Scopus subject areas

  • Computer Graphics and Computer-Aided Design
  • Hardware and Architecture
  • Software

Cite this

Hameroff, S. R., Dayhoff, J. E., Lahoz-Beltra, R., Samsonovich, A. V., & Rasmussen, S. (1992). Models for molecular computation: Conformational automata in the cytoskeleton. Computer, 25(11), 30-39. https://doi.org/10.1109/2.166406

Models for molecular computation : Conformational automata in the cytoskeleton. / Hameroff, Stuart R; Dayhoff, Judith E.; Lahoz-Beltra, Rafael; Samsonovich, Alexei V.; Rasmussen, Steen.

In: Computer, Vol. 25, No. 11, 11.1992, p. 30-39.

Research output: Contribution to journalArticle

Hameroff, SR, Dayhoff, JE, Lahoz-Beltra, R, Samsonovich, AV & Rasmussen, S 1992, 'Models for molecular computation: Conformational automata in the cytoskeleton', Computer, vol. 25, no. 11, pp. 30-39. https://doi.org/10.1109/2.166406
Hameroff SR, Dayhoff JE, Lahoz-Beltra R, Samsonovich AV, Rasmussen S. Models for molecular computation: Conformational automata in the cytoskeleton. Computer. 1992 Nov;25(11):30-39. https://doi.org/10.1109/2.166406
Hameroff, Stuart R ; Dayhoff, Judith E. ; Lahoz-Beltra, Rafael ; Samsonovich, Alexei V. ; Rasmussen, Steen. / Models for molecular computation : Conformational automata in the cytoskeleton. In: Computer. 1992 ; Vol. 25, No. 11. pp. 30-39.
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