Abstract
The purpose of the current study was to describe four models of cognitive deficit and to outline the statistical hypotheses underlying each model. The four models of cognitive deficit were (a) specific deficit; (b) subgroup deficit; (c) a syndrome dissociation model; and (d) a global function dissociation model. Neuropsychological data are analyzed to examine each of these four models in a sample of mild Multiple Sclerosis (MS) patients. The results suggest that for these subjects and tests, the specific deficit model best fits the data. The results are reviewed initially in the context of MS. There follows a consideration of statistical caveats and finally, general applications of the proposed procedures.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 563-577 |
| Number of pages | 15 |
| Journal | Journal of Clinical and Experimental Neuropsychology |
| Volume | 15 |
| Issue number | 4 |
| State | Published - 1993 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Clinical Neurology
- Neurology
- Psychology(all)
- Clinical Psychology
Cite this
Models of cognitive deficit and statistical hypotheses : Multiple sclerosis, an example. / Ryan, T Lee; Clark, C. M.; Klonoff, H.; Paty, D.
In: Journal of Clinical and Experimental Neuropsychology, Vol. 15, No. 4, 1993, p. 563-577.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Models of cognitive deficit and statistical hypotheses
T2 - Multiple sclerosis, an example
AU - Ryan, T Lee
AU - Clark, C. M.
AU - Klonoff, H.
AU - Paty, D.
PY - 1993
Y1 - 1993
N2 - The purpose of the current study was to describe four models of cognitive deficit and to outline the statistical hypotheses underlying each model. The four models of cognitive deficit were (a) specific deficit; (b) subgroup deficit; (c) a syndrome dissociation model; and (d) a global function dissociation model. Neuropsychological data are analyzed to examine each of these four models in a sample of mild Multiple Sclerosis (MS) patients. The results suggest that for these subjects and tests, the specific deficit model best fits the data. The results are reviewed initially in the context of MS. There follows a consideration of statistical caveats and finally, general applications of the proposed procedures.
AB - The purpose of the current study was to describe four models of cognitive deficit and to outline the statistical hypotheses underlying each model. The four models of cognitive deficit were (a) specific deficit; (b) subgroup deficit; (c) a syndrome dissociation model; and (d) a global function dissociation model. Neuropsychological data are analyzed to examine each of these four models in a sample of mild Multiple Sclerosis (MS) patients. The results suggest that for these subjects and tests, the specific deficit model best fits the data. The results are reviewed initially in the context of MS. There follows a consideration of statistical caveats and finally, general applications of the proposed procedures.
UR - http://www.scopus.com/inward/record.url?scp=0027290688&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027290688&partnerID=8YFLogxK
M3 - Article
C2 - 8354709
AN - SCOPUS:0027290688
VL - 15
SP - 563
EP - 577
JO - Journal of Clinical and Experimental Neuropsychology
JF - Journal of Clinical and Experimental Neuropsychology
SN - 0168-8634
IS - 4
ER -