Models of frequency preferences of prefrontal cortical neurons

Arthur R. Houweling, Rashmi H. Modi, Paul Ganter, Jean-Marc Fellous, Terrence J. Sejnowski

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The reliability of spike trains generated by sinusoidal current injections in prefrontal cortical pyramidal cells and interneurons depends strongly on the input frequency. We constructed computational models in order to study how cellular properties affect reliability. The models reproduced the main experimental findings: subthreshold oscillations, resonance and reliability of spike timing. The amplitude of intrinsic noise in the model determined the number of reliable frequency bands. In addition, the frequency content of the noise did not affect reliability.

Original languageEnglish (US)
Pages (from-to)231-238
Number of pages8
JournalNeurocomputing
Volume38-40
DOIs
StatePublished - Jun 2001
Externally publishedYes

Fingerprint

Neurons
Noise
Pyramidal Cells
Interneurons
Injections
Frequency bands

ASJC Scopus subject areas

  • Artificial Intelligence
  • Cellular and Molecular Neuroscience

Cite this

Models of frequency preferences of prefrontal cortical neurons. / R. Houweling, Arthur; H. Modi, Rashmi; Ganter, Paul; Fellous, Jean-Marc; J. Sejnowski, Terrence.

In: Neurocomputing, Vol. 38-40, 06.2001, p. 231-238.

Research output: Contribution to journalArticle

R. Houweling, A, H. Modi, R, Ganter, P, Fellous, J-M & J. Sejnowski, T 2001, 'Models of frequency preferences of prefrontal cortical neurons', Neurocomputing, vol. 38-40, pp. 231-238. https://doi.org/10.1016/S0925-2312(01)00527-6
R. Houweling, Arthur ; H. Modi, Rashmi ; Ganter, Paul ; Fellous, Jean-Marc ; J. Sejnowski, Terrence. / Models of frequency preferences of prefrontal cortical neurons. In: Neurocomputing. 2001 ; Vol. 38-40. pp. 231-238.
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