A promising technique for detoxification of certain drugs is the use of drug-specific antibody fragments (Fab, the antigen-binding fragment of IgG). This type of treatment has been shown to reverse digoxin and digitoxin toxicity rapidly in both animals and humans. The purpose of this paper is to discuss the important factors in the use of immunotherapy for treating PCP toxicity and to present preliminary data on the effects of anti-PCP Fab fragments on PCP pharmacokinetics in dogs.
|Original language||English (US)|
|Number of pages||15|
|Journal||NIDA Research Monograph Series|
|State||Published - Jan 1 1986|
ASJC Scopus subject areas
- Medicine (miscellaneous)