Molecular catch and release: Controlled delivery using optical trapping with light-responsive liposomes

Sarah J. Leung, Marek Romanowski

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.

Original languageEnglish (US)
Pages (from-to)6380-6383
Number of pages4
JournalAdvanced Materials
Volume24
Issue number47
DOIs
StatePublished - Dec 11 2012

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Keywords

  • controlled release
  • liposomes
  • nanoparticles
  • optical trapping
  • plasmon resonance

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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