Molecular layer detection on a diffractive optical balance

Xuefeng Wang, Ming Zhao, David D. Nolte

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Diffraction-based molecular detection is achieved by etching optical gratings into thermal oxide on silicon. The gratings perform as a stable common-path diffractive optical balance (DOB) designed to operate near a missing diffraction order. The biosensor is operated in an off-null condition with a phase bias to produce a high-contrast responsivity that is linear in accumulated molecules but with a low background. The DOB linear responsivity is a factor of 20 larger than the reflectometric responsivity of planar thermal oxide.

Original languageEnglish (US)
Pages (from-to)4098-4100
Number of pages3
JournalOptics letters
Issue number19
StatePublished - Oct 1 2012

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics


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