MRI of ovarian torsion: Correlation of imaging features with the presence of perifollicular hemorrhage and ovarian viability

Iva Petkovska, Eugene Duke, Diego R Martin, Zeenia Irani, Christopher P. Geffre, Janiel M. Cragun, James R. Costello, Hina Arif-Tiwari, Ferenc Czeyda-Pommersheim, Unni Udayasankar, Bobby T Kalb

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose The purpose of our study is to test for: (a) correlation between the presence of a perifollicular T2-hypointense rim on MRI with the presence of perifollicular hemorrhage on histology; and (b) correlation between this finding and diminished ovarian viability after intra-operative detorsion. Methods and materials Our IRB-approved, retrospective study evaluated 780 patients between August 2012 and February 2016 with ovarian torsion as a diagnostic consideration on the emergency department note. Patients were included if they had preoperative MRI and intraoperatively confirmed case of ovarian torsion. MRIs were retrospectively reviewed for presence of perifollicular T2 hypointense rim in the torsed ovary. Two arms of analysis were performed: (a) assessment of perifollicular hemorrhage on histological exam; and (b) assessment of ovarian viability after intra-operative detorsion. Sensitivity, specificity, positive predictive value, and negative predictive value of MRI for predicting ovarian viability in the setting of torsion was performed. κ test assessed level of agreement between readers. Results 24 patients included in one of the two arms; 20 in viability analysis and 12 in perifollicular hemorrhage analysis (8 in both). The presence of T2-hypointense rim on MRI demonstrated 88.9% sensitivity and 66.7% specificity for the diagnosis of perifollicular hemorrhage on histology, and 91.7% sensitivity and 100% specificity for predicting intraoperative viability. Conclusion The presence of a perifollicular T2 hypointense rim on MRI in the setting of ovarian torsion correlates with perifollicular hemorrhage on histopathologic exam, and may also be a useful predictor of ovarian viability in patients presenting with ovarian torsion.

Original languageEnglish (US)
Pages (from-to)2064-2071
Number of pages8
JournalEuropean Journal of Radiology
Volume85
Issue number11
DOIs
StatePublished - Nov 1 2016

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Hemorrhage
Sensitivity and Specificity
Histology
Research Ethics Committees
Hospital Emergency Service
Ovary
Retrospective Studies

Keywords

  • Body MRI
  • Emergency medicine
  • Ovarian torsion
  • Ovarian viability

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

MRI of ovarian torsion : Correlation of imaging features with the presence of perifollicular hemorrhage and ovarian viability. / Petkovska, Iva; Duke, Eugene; Martin, Diego R; Irani, Zeenia; Geffre, Christopher P.; Cragun, Janiel M.; Costello, James R.; Arif-Tiwari, Hina; Czeyda-Pommersheim, Ferenc; Udayasankar, Unni; Kalb, Bobby T.

In: European Journal of Radiology, Vol. 85, No. 11, 01.11.2016, p. 2064-2071.

Research output: Contribution to journalArticle

Petkovska, I, Duke, E, Martin, DR, Irani, Z, Geffre, CP, Cragun, JM, Costello, JR, Arif-Tiwari, H, Czeyda-Pommersheim, F, Udayasankar, U & Kalb, BT 2016, 'MRI of ovarian torsion: Correlation of imaging features with the presence of perifollicular hemorrhage and ovarian viability', European Journal of Radiology, vol. 85, no. 11, pp. 2064-2071. https://doi.org/10.1016/j.ejrad.2016.09.020
Petkovska, Iva ; Duke, Eugene ; Martin, Diego R ; Irani, Zeenia ; Geffre, Christopher P. ; Cragun, Janiel M. ; Costello, James R. ; Arif-Tiwari, Hina ; Czeyda-Pommersheim, Ferenc ; Udayasankar, Unni ; Kalb, Bobby T. / MRI of ovarian torsion : Correlation of imaging features with the presence of perifollicular hemorrhage and ovarian viability. In: European Journal of Radiology. 2016 ; Vol. 85, No. 11. pp. 2064-2071.
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abstract = "Purpose The purpose of our study is to test for: (a) correlation between the presence of a perifollicular T2-hypointense rim on MRI with the presence of perifollicular hemorrhage on histology; and (b) correlation between this finding and diminished ovarian viability after intra-operative detorsion. Methods and materials Our IRB-approved, retrospective study evaluated 780 patients between August 2012 and February 2016 with ovarian torsion as a diagnostic consideration on the emergency department note. Patients were included if they had preoperative MRI and intraoperatively confirmed case of ovarian torsion. MRIs were retrospectively reviewed for presence of perifollicular T2 hypointense rim in the torsed ovary. Two arms of analysis were performed: (a) assessment of perifollicular hemorrhage on histological exam; and (b) assessment of ovarian viability after intra-operative detorsion. Sensitivity, specificity, positive predictive value, and negative predictive value of MRI for predicting ovarian viability in the setting of torsion was performed. κ test assessed level of agreement between readers. Results 24 patients included in one of the two arms; 20 in viability analysis and 12 in perifollicular hemorrhage analysis (8 in both). The presence of T2-hypointense rim on MRI demonstrated 88.9{\%} sensitivity and 66.7{\%} specificity for the diagnosis of perifollicular hemorrhage on histology, and 91.7{\%} sensitivity and 100{\%} specificity for predicting intraoperative viability. Conclusion The presence of a perifollicular T2 hypointense rim on MRI in the setting of ovarian torsion correlates with perifollicular hemorrhage on histopathologic exam, and may also be a useful predictor of ovarian viability in patients presenting with ovarian torsion.",
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T2 - Correlation of imaging features with the presence of perifollicular hemorrhage and ovarian viability

AU - Petkovska, Iva

AU - Duke, Eugene

AU - Martin, Diego R

AU - Irani, Zeenia

AU - Geffre, Christopher P.

AU - Cragun, Janiel M.

AU - Costello, James R.

AU - Arif-Tiwari, Hina

AU - Czeyda-Pommersheim, Ferenc

AU - Udayasankar, Unni

AU - Kalb, Bobby T

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Purpose The purpose of our study is to test for: (a) correlation between the presence of a perifollicular T2-hypointense rim on MRI with the presence of perifollicular hemorrhage on histology; and (b) correlation between this finding and diminished ovarian viability after intra-operative detorsion. Methods and materials Our IRB-approved, retrospective study evaluated 780 patients between August 2012 and February 2016 with ovarian torsion as a diagnostic consideration on the emergency department note. Patients were included if they had preoperative MRI and intraoperatively confirmed case of ovarian torsion. MRIs were retrospectively reviewed for presence of perifollicular T2 hypointense rim in the torsed ovary. Two arms of analysis were performed: (a) assessment of perifollicular hemorrhage on histological exam; and (b) assessment of ovarian viability after intra-operative detorsion. Sensitivity, specificity, positive predictive value, and negative predictive value of MRI for predicting ovarian viability in the setting of torsion was performed. κ test assessed level of agreement between readers. Results 24 patients included in one of the two arms; 20 in viability analysis and 12 in perifollicular hemorrhage analysis (8 in both). The presence of T2-hypointense rim on MRI demonstrated 88.9% sensitivity and 66.7% specificity for the diagnosis of perifollicular hemorrhage on histology, and 91.7% sensitivity and 100% specificity for predicting intraoperative viability. Conclusion The presence of a perifollicular T2 hypointense rim on MRI in the setting of ovarian torsion correlates with perifollicular hemorrhage on histopathologic exam, and may also be a useful predictor of ovarian viability in patients presenting with ovarian torsion.

AB - Purpose The purpose of our study is to test for: (a) correlation between the presence of a perifollicular T2-hypointense rim on MRI with the presence of perifollicular hemorrhage on histology; and (b) correlation between this finding and diminished ovarian viability after intra-operative detorsion. Methods and materials Our IRB-approved, retrospective study evaluated 780 patients between August 2012 and February 2016 with ovarian torsion as a diagnostic consideration on the emergency department note. Patients were included if they had preoperative MRI and intraoperatively confirmed case of ovarian torsion. MRIs were retrospectively reviewed for presence of perifollicular T2 hypointense rim in the torsed ovary. Two arms of analysis were performed: (a) assessment of perifollicular hemorrhage on histological exam; and (b) assessment of ovarian viability after intra-operative detorsion. Sensitivity, specificity, positive predictive value, and negative predictive value of MRI for predicting ovarian viability in the setting of torsion was performed. κ test assessed level of agreement between readers. Results 24 patients included in one of the two arms; 20 in viability analysis and 12 in perifollicular hemorrhage analysis (8 in both). The presence of T2-hypointense rim on MRI demonstrated 88.9% sensitivity and 66.7% specificity for the diagnosis of perifollicular hemorrhage on histology, and 91.7% sensitivity and 100% specificity for predicting intraoperative viability. Conclusion The presence of a perifollicular T2 hypointense rim on MRI in the setting of ovarian torsion correlates with perifollicular hemorrhage on histopathologic exam, and may also be a useful predictor of ovarian viability in patients presenting with ovarian torsion.

KW - Body MRI

KW - Emergency medicine

KW - Ovarian torsion

KW - Ovarian viability

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