Multiple release of equimolar amounts of peptides from a polymeric carrier using orthogonal linkage‐cleavage chemistry

MICHAL LEBL, MARCEL PÁTEK, PETR KOČIŠ, VIKTOR KRCHŇÁK, VICTOR J. HRUBY, SYDNEY E. SALMON, KITS LAM

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

Peptides generated on polymeric beads that are attached to the support via cleavable linkers are released into solution in equimolar amounts in several independent steps and screening of the “peptide libraries” can be performed in the usual manner used for testing peptides in solution.

Original languageEnglish (US)
Pages (from-to)201-203
Number of pages3
JournalInternational journal of peptide and protein research
Volume41
Issue number2
DOIs
StatePublished - Feb 1993

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Keywords

  • independently cleavable linkers
  • multicleavable linkers
  • peptide libraries
  • solid phase synthesis

ASJC Scopus subject areas

  • Biochemistry

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