Mutations in FIE, a WD polycomb group gene, allow endosperm development without fertilization

Nir Ohad, Ramin Yadegari, Linda Margossian, Mike Hannon, Daphna Michaeli, John J. Harada, Robert B. Goldberg, Robert L. Fischer

Research output: Contribution to journalArticle

322 Scopus citations

Abstract

A fundamental problem in biology is to understand how fertilization initiates reproductive development. Higher plant reproduction is unique because two fertilization events are required for sexual reproduction. First, a sperm must fuse with the egg to form an embryo. A second sperm must then fuse with the adjacent central cell nucleus that replicates to form an endosperm, which is the support tissue required for embryo and/or seedling development. Here, we report cloning of the Arabidopsis FERTILIZATION-INDEPENDENT ENDOSPERM (FIE) gene. The FIE protein is a homolog of the WD motif-containing Polycomb proteins from Drosophila and mammals. These proteins function as repressers of homeotic genes. A female gametophyte with a loss-of-function allele of fie undergoes replication of the central cell nucleus and initiates endosperm development without fertilization. These results suggest that the FIE Polycomb protein functions to suppress a critical aspect of early plant reproduction, namely, endosperm development, until fertilization occurs.

Original languageEnglish (US)
Pages (from-to)407-415
Number of pages9
JournalPlant Cell
Volume11
Issue number3
DOIs
StatePublished - Mar 1 1999
Externally publishedYes

ASJC Scopus subject areas

  • Plant Science
  • Cell Biology

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    Ohad, N., Yadegari, R., Margossian, L., Hannon, M., Michaeli, D., Harada, J. J., Goldberg, R. B., & Fischer, R. L. (1999). Mutations in FIE, a WD polycomb group gene, allow endosperm development without fertilization. Plant Cell, 11(3), 407-415. https://doi.org/10.1105/tpc.11.3.407