Myelodysplastic transformation of polycythemia vera: Case report and review of the literature

Glenn J. Shamdas, Catherine M. Spier, Alan F. List

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

We report a case of refractory anemia with excess blasts (RAEB) developing in a 67‐year old man with a history of polycythemia vera; results of cytogenetic and immunophenotyping studies are described. In this report the clinical, cytogenetic and hematologic features of myelodysplasia complicating polycythemia vera are reviewed. Results of immunophenotyping and cytogenetic studies, and the preponderance of cases developing after myelosuppressive therapy suggest that in the majority of cases myelodysplasia is treatment‐related.

Original languageEnglish (US)
Pages (from-to)45-48
Number of pages4
JournalAmerican Journal of Hematology
Volume37
Issue number1
DOIs
StatePublished - May 1991
Externally publishedYes

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Keywords

  • cytogenic studies
  • immunophenotyping studies
  • myelodysplastic syndrome
  • polycythemia vera

ASJC Scopus subject areas

  • Hematology

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