Nanofibrous lipid membranes capable of functionally immobilizing antibodies and capturing specific cells

Zhengbao Zha, Celine Cohn, Zhifei Dai, Weiguo Qiu, Jinhong Zhang, Xiaoyi Wu

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Polymerizable cholesteryl-succinyl silane was synthesized and fabricated into stable nanofibrous lipid membranes using a combined sol-gel and electrospinning process. The resulting nanofibrous lipid membranes are capable of functionally immobilizing membrane proteins such as antibodies, thereby enabling targeted cell capture via the antigen-antibody interactions.

Original languageEnglish (US)
Pages (from-to)3435-3440
Number of pages6
JournalAdvanced Materials
Volume23
Issue number30
DOIs
StatePublished - Aug 9 2011

Keywords

  • Lipid nanofibers
  • antibody immobilization
  • cell capture
  • cholesterol

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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