Nanopharmaceuticals I

Nanocarrier systems in drug delivery

Yun Seok Rhee, Heidi - Mansour

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

To achieve maximum pharmacological effects with minimum side effects of drugs, drugs should be delivered to target sites without significant distribution to non-target areas. Using pharmaceutical nanocarrier systems for drug delivery is a useful delivery platform for improving target specificity, therapeutic activity, and reducing toxicity of drugs. Various sophisticated nanocarrier systems have been developed for drug delivery, and this review focuses on liposomes, polymeric nanoparticles, polymeric micelles, lipid nanoparticles, microemulsions, nanogels, and submicron lipid emulsions. This review outlines and explores nanocarrier systems for drug delivery by various administration routes including parenteral, oral, transdermal, pulmonary, ocular, and mucosal and discusses the product development and related issues in nanopharmaceutical drug delivery.

Original languageEnglish (US)
Pages (from-to)84-114
Number of pages31
JournalInternational Journal of Nanotechnology
Volume8
Issue number1-2
DOIs
StatePublished - 2011
Externally publishedYes

Fingerprint

Drug delivery
delivery
drugs
Pharmaceutical Preparations
Lipids
Nanoparticles
Liposomes
Microemulsions
Micelles
Emulsions
lipids
Product development
Drug products
Toxicity
nanoparticles
product development
toxicity
emulsions
micelles
platforms

Keywords

  • Lipid nanoparticles
  • Liposomes
  • Microemulsions
  • Nanogels
  • Polymeric micelles
  • Polymeric nanoparticles
  • Submicron lipid emulsions

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Materials Chemistry
  • Condensed Matter Physics
  • Bioengineering

Cite this

Nanopharmaceuticals I : Nanocarrier systems in drug delivery. / Rhee, Yun Seok; Mansour, Heidi -.

In: International Journal of Nanotechnology, Vol. 8, No. 1-2, 2011, p. 84-114.

Research output: Contribution to journalArticle

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