National cancer institute prostate cancer genetics workshop

William J. Catalona, Joan E. Bailey-Wilson, Nicola J. Camp, Stephen J. Chanock, Kathleen A. Cooney, Douglas F. Easton, Rosalind A. Eeles, Liesel M. FitzGerald, Matthew L. Freedman, Julius Gudmundsson, Rick A Kittles, Elliott H. Margulies, Barry B. McGuire, Elaine A. Ostrander, Timothy R. Rebbeck, Janet L. Stanford, Stephen N. Thibodeau, John S. Witte, William B. Isaacs

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Compelling evidence supports a genetic component to prostate cancer susceptibility and aggressiveness. Recent genome-wide association studies have identified more than 30 single-nucleotide polymorphisms associated with prostate cancer susceptibility. It remains unclear, however, whether such genetic variants are associated with disease aggressiveness-one of themost important questions in prostate cancer research today. To help clarify this and substantially expand research in the genetic determinants of prostate cancer aggressiveness, the first National Cancer Institute Prostate Cancer Genetics Workshop assembled researchers to develop plans for a large new research consortium and patient cohort. The workshop reviewed the prior work in this area and addressed the practical issues in planning future studies. With new DNA sequencing technology, the potential application of sequencing information to patient care is emerging. The workshop, therefore, included state-of-the-art presentations by experts on new genotyping technologies, including sequencing and associated bioinformatics issues, which are just beginning to be applied to cancer genetics.

Original languageEnglish (US)
Pages (from-to)3442-3446
Number of pages5
JournalCancer Research
Volume71
Issue number10
DOIs
StatePublished - May 15 2011
Externally publishedYes

Fingerprint

National Cancer Institute (U.S.)
Prostatic Neoplasms
Education
Technology
Genetic Research
Genome-Wide Association Study
Computational Biology
DNA Sequence Analysis
Research
Single Nucleotide Polymorphism
Patient Care
Research Personnel
Neoplasms
Prostate Cancer, Hereditary, 7

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Catalona, W. J., Bailey-Wilson, J. E., Camp, N. J., Chanock, S. J., Cooney, K. A., Easton, D. F., ... Isaacs, W. B. (2011). National cancer institute prostate cancer genetics workshop. Cancer Research, 71(10), 3442-3446. https://doi.org/10.1158/0008-5472.CAN-11-0314

National cancer institute prostate cancer genetics workshop. / Catalona, William J.; Bailey-Wilson, Joan E.; Camp, Nicola J.; Chanock, Stephen J.; Cooney, Kathleen A.; Easton, Douglas F.; Eeles, Rosalind A.; FitzGerald, Liesel M.; Freedman, Matthew L.; Gudmundsson, Julius; Kittles, Rick A; Margulies, Elliott H.; McGuire, Barry B.; Ostrander, Elaine A.; Rebbeck, Timothy R.; Stanford, Janet L.; Thibodeau, Stephen N.; Witte, John S.; Isaacs, William B.

In: Cancer Research, Vol. 71, No. 10, 15.05.2011, p. 3442-3446.

Research output: Contribution to journalArticle

Catalona, WJ, Bailey-Wilson, JE, Camp, NJ, Chanock, SJ, Cooney, KA, Easton, DF, Eeles, RA, FitzGerald, LM, Freedman, ML, Gudmundsson, J, Kittles, RA, Margulies, EH, McGuire, BB, Ostrander, EA, Rebbeck, TR, Stanford, JL, Thibodeau, SN, Witte, JS & Isaacs, WB 2011, 'National cancer institute prostate cancer genetics workshop', Cancer Research, vol. 71, no. 10, pp. 3442-3446. https://doi.org/10.1158/0008-5472.CAN-11-0314
Catalona WJ, Bailey-Wilson JE, Camp NJ, Chanock SJ, Cooney KA, Easton DF et al. National cancer institute prostate cancer genetics workshop. Cancer Research. 2011 May 15;71(10):3442-3446. https://doi.org/10.1158/0008-5472.CAN-11-0314
Catalona, William J. ; Bailey-Wilson, Joan E. ; Camp, Nicola J. ; Chanock, Stephen J. ; Cooney, Kathleen A. ; Easton, Douglas F. ; Eeles, Rosalind A. ; FitzGerald, Liesel M. ; Freedman, Matthew L. ; Gudmundsson, Julius ; Kittles, Rick A ; Margulies, Elliott H. ; McGuire, Barry B. ; Ostrander, Elaine A. ; Rebbeck, Timothy R. ; Stanford, Janet L. ; Thibodeau, Stephen N. ; Witte, John S. ; Isaacs, William B. / National cancer institute prostate cancer genetics workshop. In: Cancer Research. 2011 ; Vol. 71, No. 10. pp. 3442-3446.
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