Natural language processing and visualization in the molecular imaging domain

P. Karina Tulipano, Ying Tao, William S. Millar, Pat Zanzonico, Katherine Kolbert, Hua Xu, Hong Yu, Lifeng Chen, Yves A Lussier, Carol Friedman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Molecular imaging is at the crossroads of genomic sciences and medical imaging. Information within the molecular imaging literature could be used to link to genomic and imaging information resources and to organize and index images in a way that is potentially useful to researchers. A number of natural language processing (NLP) systems are available to automatically extract information from genomic literature. One existing NLP system, known as BioMedLEE, automatically extracts biological information consisting of biomolecular substances and phenotypic data. This paper focuses on the adaptation, evaluation, and application of BioMedLEE to the molecular imaging domain. In order to adapt BioMedLEE for this domain, we extend an existing molecular imaging terminology and incorporate it into BioMedLEE. BioMedLEE's performance is assessed with a formal evaluation study. The system's performance, measured as recall and precision, is 0.74 (95% CI: [.70-.76]) and 0.70 (95% CI [.63-.76]), respectively. We adapt a JAVA™ viewer known as PGviewer for the simultaneous visualization of images with NLP extracted information.

Original languageEnglish (US)
Pages (from-to)270-281
Number of pages12
JournalJournal of Biomedical Informatics
Volume40
Issue number3
DOIs
StatePublished - Jun 2007
Externally publishedYes

Fingerprint

Natural Language Processing
Molecular imaging
Molecular Imaging
Natural language processing systems
Visualization
Processing
Medical imaging
Diagnostic Imaging
Terminology
Research Personnel
Imaging techniques

Keywords

  • BioMedLEE
  • GeneWays
  • Information extraction
  • Molecular imaging
  • Natural language processing
  • Ontologies
  • PGviewer

ASJC Scopus subject areas

  • Computer Science Applications
  • Health Informatics
  • Computer Science (miscellaneous)
  • Catalysis

Cite this

Karina Tulipano, P., Tao, Y., Millar, W. S., Zanzonico, P., Kolbert, K., Xu, H., ... Friedman, C. (2007). Natural language processing and visualization in the molecular imaging domain. Journal of Biomedical Informatics, 40(3), 270-281. https://doi.org/10.1016/j.jbi.2006.08.002

Natural language processing and visualization in the molecular imaging domain. / Karina Tulipano, P.; Tao, Ying; Millar, William S.; Zanzonico, Pat; Kolbert, Katherine; Xu, Hua; Yu, Hong; Chen, Lifeng; Lussier, Yves A; Friedman, Carol.

In: Journal of Biomedical Informatics, Vol. 40, No. 3, 06.2007, p. 270-281.

Research output: Contribution to journalArticle

Karina Tulipano, P, Tao, Y, Millar, WS, Zanzonico, P, Kolbert, K, Xu, H, Yu, H, Chen, L, Lussier, YA & Friedman, C 2007, 'Natural language processing and visualization in the molecular imaging domain', Journal of Biomedical Informatics, vol. 40, no. 3, pp. 270-281. https://doi.org/10.1016/j.jbi.2006.08.002
Karina Tulipano P, Tao Y, Millar WS, Zanzonico P, Kolbert K, Xu H et al. Natural language processing and visualization in the molecular imaging domain. Journal of Biomedical Informatics. 2007 Jun;40(3):270-281. https://doi.org/10.1016/j.jbi.2006.08.002
Karina Tulipano, P. ; Tao, Ying ; Millar, William S. ; Zanzonico, Pat ; Kolbert, Katherine ; Xu, Hua ; Yu, Hong ; Chen, Lifeng ; Lussier, Yves A ; Friedman, Carol. / Natural language processing and visualization in the molecular imaging domain. In: Journal of Biomedical Informatics. 2007 ; Vol. 40, No. 3. pp. 270-281.
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