Negative pressure wound therapy and other new therapies for diabetic foot ulceration: The current state of play

Adam L. Isaac, David G. Armstrong

Research output: Contribution to journalReview article

21 Scopus citations


Up to 25% of people with diabetes will develop a foot ulcer, with 1 in 5 ulcers requiring an amputation. An interdisciplinary team approach to limb salvage, combined with a vertical and horizontal strategy for wound healing, may help to systematically simplify what is a complex process. The organization and integration of care, with an emphasis placed on identifying key diagnostic points in healing and warning signs for recurrence, will be instrumental in improving outcomes in patients with diabetes and complicated foot wounds.

Original languageEnglish (US)
Pages (from-to)899-909
Number of pages11
JournalMedical Clinics of North America
Issue number5
StatePublished - Sep 1 2013



  • Diabetic foot ulcer
  • Negative pressure wound therapy
  • Theragnostics
  • Wound chemotherapy

ASJC Scopus subject areas

  • Medicine(all)

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