Neural substrates of sublexical processing for spelling

Andrew T. DeMarco, Stephen M Wilson, Kindle Rising, Steven Z Rapcsak, Pelagie M Beeson

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We used fMRI to examine the neural substrates of sublexical phoneme-grapheme conversion during spelling in a group of healthy young adults. Participants performed a writing-to-dictation task involving irregular words (e.g., choir), plausible nonwords (e.g., kroid), and a control task of drawing familiar geometric shapes (e.g., squares). Written production of both irregular words and nonwords engaged a left-hemisphere perisylvian network associated with reading/spelling and phonological processing skills. Effects of lexicality, manifested by increased activation during nonword relative to irregular word spelling, were noted in anterior perisylvian regions (posterior inferior frontal gyrus/operculum/precentral gyrus/insula), and in left ventral occipito-temporal cortex. In addition to enhanced neural responses within domain-specific components of the language network, the increased cognitive demands associated with spelling nonwords engaged domain-general frontoparietal cortical networks involved in selective attention and executive control. These results elucidate the neural substrates of sublexical processing during written language production and complement lesion-deficit correlation studies of phonological agraphia.

Original languageEnglish (US)
Pages (from-to)118-128
Number of pages11
JournalBrain and Language
Volume164
DOIs
StatePublished - Jan 1 2017

Fingerprint

Language
Agraphia
Executive Function
Frontal Lobe
Temporal Lobe
Prefrontal Cortex
Reading
Young Adult
written language
Magnetic Resonance Imaging
activation
young adult
deficit
language
Substrate
Spelling
Nonwords
Sublexical Processing
Group
Irregular

Keywords

  • fMRI
  • Phonological agraphia
  • Phonological processing
  • Spelling
  • Sublexical processing
  • Writing

ASJC Scopus subject areas

  • Language and Linguistics
  • Experimental and Cognitive Psychology
  • Linguistics and Language
  • Cognitive Neuroscience
  • Speech and Hearing

Cite this

Neural substrates of sublexical processing for spelling. / DeMarco, Andrew T.; Wilson, Stephen M; Rising, Kindle; Rapcsak, Steven Z; Beeson, Pelagie M.

In: Brain and Language, Vol. 164, 01.01.2017, p. 118-128.

Research output: Contribution to journalArticle

@article{2246336dcb134465b1a10428f2afde4d,
title = "Neural substrates of sublexical processing for spelling",
abstract = "We used fMRI to examine the neural substrates of sublexical phoneme-grapheme conversion during spelling in a group of healthy young adults. Participants performed a writing-to-dictation task involving irregular words (e.g., choir), plausible nonwords (e.g., kroid), and a control task of drawing familiar geometric shapes (e.g., squares). Written production of both irregular words and nonwords engaged a left-hemisphere perisylvian network associated with reading/spelling and phonological processing skills. Effects of lexicality, manifested by increased activation during nonword relative to irregular word spelling, were noted in anterior perisylvian regions (posterior inferior frontal gyrus/operculum/precentral gyrus/insula), and in left ventral occipito-temporal cortex. In addition to enhanced neural responses within domain-specific components of the language network, the increased cognitive demands associated with spelling nonwords engaged domain-general frontoparietal cortical networks involved in selective attention and executive control. These results elucidate the neural substrates of sublexical processing during written language production and complement lesion-deficit correlation studies of phonological agraphia.",
keywords = "fMRI, Phonological agraphia, Phonological processing, Spelling, Sublexical processing, Writing",
author = "DeMarco, {Andrew T.} and Wilson, {Stephen M} and Kindle Rising and Rapcsak, {Steven Z} and Beeson, {Pelagie M}",
year = "2017",
month = "1",
day = "1",
doi = "10.1016/j.bandl.2016.10.001",
language = "English (US)",
volume = "164",
pages = "118--128",
journal = "Brain and Language",
issn = "0093-934X",
publisher = "Academic Press Inc.",

}

TY - JOUR

T1 - Neural substrates of sublexical processing for spelling

AU - DeMarco, Andrew T.

AU - Wilson, Stephen M

AU - Rising, Kindle

AU - Rapcsak, Steven Z

AU - Beeson, Pelagie M

PY - 2017/1/1

Y1 - 2017/1/1

N2 - We used fMRI to examine the neural substrates of sublexical phoneme-grapheme conversion during spelling in a group of healthy young adults. Participants performed a writing-to-dictation task involving irregular words (e.g., choir), plausible nonwords (e.g., kroid), and a control task of drawing familiar geometric shapes (e.g., squares). Written production of both irregular words and nonwords engaged a left-hemisphere perisylvian network associated with reading/spelling and phonological processing skills. Effects of lexicality, manifested by increased activation during nonword relative to irregular word spelling, were noted in anterior perisylvian regions (posterior inferior frontal gyrus/operculum/precentral gyrus/insula), and in left ventral occipito-temporal cortex. In addition to enhanced neural responses within domain-specific components of the language network, the increased cognitive demands associated with spelling nonwords engaged domain-general frontoparietal cortical networks involved in selective attention and executive control. These results elucidate the neural substrates of sublexical processing during written language production and complement lesion-deficit correlation studies of phonological agraphia.

AB - We used fMRI to examine the neural substrates of sublexical phoneme-grapheme conversion during spelling in a group of healthy young adults. Participants performed a writing-to-dictation task involving irregular words (e.g., choir), plausible nonwords (e.g., kroid), and a control task of drawing familiar geometric shapes (e.g., squares). Written production of both irregular words and nonwords engaged a left-hemisphere perisylvian network associated with reading/spelling and phonological processing skills. Effects of lexicality, manifested by increased activation during nonword relative to irregular word spelling, were noted in anterior perisylvian regions (posterior inferior frontal gyrus/operculum/precentral gyrus/insula), and in left ventral occipito-temporal cortex. In addition to enhanced neural responses within domain-specific components of the language network, the increased cognitive demands associated with spelling nonwords engaged domain-general frontoparietal cortical networks involved in selective attention and executive control. These results elucidate the neural substrates of sublexical processing during written language production and complement lesion-deficit correlation studies of phonological agraphia.

KW - fMRI

KW - Phonological agraphia

KW - Phonological processing

KW - Spelling

KW - Sublexical processing

KW - Writing

UR - http://www.scopus.com/inward/record.url?scp=85010209008&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85010209008&partnerID=8YFLogxK

U2 - 10.1016/j.bandl.2016.10.001

DO - 10.1016/j.bandl.2016.10.001

M3 - Article

C2 - 27838547

AN - SCOPUS:85010209008

VL - 164

SP - 118

EP - 128

JO - Brain and Language

JF - Brain and Language

SN - 0093-934X

ER -