Neuroleptic-mediated hypothalamic deregulation of central insulin and peripheral glucose metabolism in tardive dyskinesia: A hypothesis

Reuven Sandyk, Colin R. Bamford

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

In the following communication we discuss evidence that impaired peripheral and central glucose and insulin metabolism may be significant in the pathophysiology of neuroleptic-induced tardive dyskinesia. Such an association between alterations in glucose metabolism and pathophysiology of tardive dyskinesia may open new avenues in the prevention and pharmacological management of this often therapy-resistant chronic neurological disorder.

Original languageEnglish (US)
Pages (from-to)213-216
Number of pages4
JournalInternational Journal of Neuroscience
Volume40
Issue number3-4
DOIs
StatePublished - Jan 1 1988

Keywords

  • Anti-diabetic agents
  • Diabetes
  • Glucose metabolism
  • Hypothalamic glucose regulation
  • Tardive dyskinesia

ASJC Scopus subject areas

  • Neuroscience(all)

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