Neuropeptides and peptide hormones in Anopheles gambiae

Michael A Riehle, Stephen F. Garczynski, Joe W. Crim, Catherine A. Hill, Mark R. Brown

Research output: Contribution to journalArticle

223 Citations (Scopus)

Abstract

The African malaria mosquito, Anopheles gambiae, is specialized for rapid completion of development and reproduction. A vertebrate blood meal is required for egg production, and multiple feedings subsequently allow transmission of malaria parasites, Plasmodium spp. Regulatory peptides from 35 genes annotated from the A. gambiae genome likely coordinate these and other physiological processes. Plasmodium parasites may affect actions of newly identified insulin-like peptides, which coordinate growth and reproduction of its vector, A. gambiae, as in Drosophila melanogaster, Caenorhabditis elegans, and mammals. This genomic information provides a basis to expand understanding of hematophagy and pathogen transmission in this mosquito.

Original languageEnglish (US)
Pages (from-to)172-175
Number of pages4
JournalScience
Volume298
Issue number5591
DOIs
StatePublished - Oct 4 2002
Externally publishedYes

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Anopheles gambiae
Peptide Hormones
Neuropeptides
Culicidae
Reproduction
Parasites
Plasmodium malariae
Physiological Phenomena
Peptides
Infectious Disease Transmission
Plasmodium
Caenorhabditis elegans
Drosophila melanogaster
Malaria
Ovum
Meals
Vertebrates
Mammals
Genome
Insulin

ASJC Scopus subject areas

  • General

Cite this

Riehle, M. A., Garczynski, S. F., Crim, J. W., Hill, C. A., & Brown, M. R. (2002). Neuropeptides and peptide hormones in Anopheles gambiae. Science, 298(5591), 172-175. https://doi.org/10.1126/science.1076827

Neuropeptides and peptide hormones in Anopheles gambiae. / Riehle, Michael A; Garczynski, Stephen F.; Crim, Joe W.; Hill, Catherine A.; Brown, Mark R.

In: Science, Vol. 298, No. 5591, 04.10.2002, p. 172-175.

Research output: Contribution to journalArticle

Riehle, MA, Garczynski, SF, Crim, JW, Hill, CA & Brown, MR 2002, 'Neuropeptides and peptide hormones in Anopheles gambiae', Science, vol. 298, no. 5591, pp. 172-175. https://doi.org/10.1126/science.1076827
Riehle MA, Garczynski SF, Crim JW, Hill CA, Brown MR. Neuropeptides and peptide hormones in Anopheles gambiae. Science. 2002 Oct 4;298(5591):172-175. https://doi.org/10.1126/science.1076827
Riehle, Michael A ; Garczynski, Stephen F. ; Crim, Joe W. ; Hill, Catherine A. ; Brown, Mark R. / Neuropeptides and peptide hormones in Anopheles gambiae. In: Science. 2002 ; Vol. 298, No. 5591. pp. 172-175.
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