Neuropsychologic function in toddlers exposed to cocaine in utero: A preliminary study

Kimberly Andrews Espy, Paul M. Kaufmann, Martha L. Glisky

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Patterns of neuropsychological performance on A-not-B, inhibition, motor, cognitive, language, and behavior tasks were examined in 34 toddlers- 17 cocaine-exposed (CE) and 17 nonexposed (NE) controls. CE toddlers exhibited greater perseveration, less inhibition, poorer emotional regulation, and less task orientation relative to NE toddlers. Overall cognitive and language skills and motor impairment status were comparable among CE and NE toddlers. Differences in perseveration, emotional regulation, and task orientation between CE and NE toddlers remained significant after statistically controlling for overall cognitive skill. Prenatal cocaine exposure may impart selective vulnerability for deficits in executive function, inhibition, and emotional regulation in toddlers, perhaps related to the concurrent rapid frontal lobe maturation and the neurobiology of cocaine. Furthermore, these findings suggest that performance can be broken down into meaningful neuropsychological components in very young children.

Original languageEnglish (US)
Pages (from-to)447-460
Number of pages14
JournalDevelopmental Neuropsychology
Volume15
Issue number3
StatePublished - 1999
Externally publishedYes

Fingerprint

Cocaine
Language
Motor Skills
Neurobiology
Executive Function
Frontal Lobe
Inhibition (Psychology)

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Psychology(all)
  • Developmental and Educational Psychology
  • Experimental and Cognitive Psychology

Cite this

Neuropsychologic function in toddlers exposed to cocaine in utero : A preliminary study. / Espy, Kimberly Andrews; Kaufmann, Paul M.; Glisky, Martha L.

In: Developmental Neuropsychology, Vol. 15, No. 3, 1999, p. 447-460.

Research output: Contribution to journalArticle

@article{e311f58bcb044c46883fbe39485318e1,
title = "Neuropsychologic function in toddlers exposed to cocaine in utero: A preliminary study",
abstract = "Patterns of neuropsychological performance on A-not-B, inhibition, motor, cognitive, language, and behavior tasks were examined in 34 toddlers- 17 cocaine-exposed (CE) and 17 nonexposed (NE) controls. CE toddlers exhibited greater perseveration, less inhibition, poorer emotional regulation, and less task orientation relative to NE toddlers. Overall cognitive and language skills and motor impairment status were comparable among CE and NE toddlers. Differences in perseveration, emotional regulation, and task orientation between CE and NE toddlers remained significant after statistically controlling for overall cognitive skill. Prenatal cocaine exposure may impart selective vulnerability for deficits in executive function, inhibition, and emotional regulation in toddlers, perhaps related to the concurrent rapid frontal lobe maturation and the neurobiology of cocaine. Furthermore, these findings suggest that performance can be broken down into meaningful neuropsychological components in very young children.",
author = "Espy, {Kimberly Andrews} and Kaufmann, {Paul M.} and Glisky, {Martha L.}",
year = "1999",
language = "English (US)",
volume = "15",
pages = "447--460",
journal = "Developmental Neuropsychology",
issn = "8756-5641",
publisher = "Psychology Press Ltd",
number = "3",

}

TY - JOUR

T1 - Neuropsychologic function in toddlers exposed to cocaine in utero

T2 - A preliminary study

AU - Espy, Kimberly Andrews

AU - Kaufmann, Paul M.

AU - Glisky, Martha L.

PY - 1999

Y1 - 1999

N2 - Patterns of neuropsychological performance on A-not-B, inhibition, motor, cognitive, language, and behavior tasks were examined in 34 toddlers- 17 cocaine-exposed (CE) and 17 nonexposed (NE) controls. CE toddlers exhibited greater perseveration, less inhibition, poorer emotional regulation, and less task orientation relative to NE toddlers. Overall cognitive and language skills and motor impairment status were comparable among CE and NE toddlers. Differences in perseveration, emotional regulation, and task orientation between CE and NE toddlers remained significant after statistically controlling for overall cognitive skill. Prenatal cocaine exposure may impart selective vulnerability for deficits in executive function, inhibition, and emotional regulation in toddlers, perhaps related to the concurrent rapid frontal lobe maturation and the neurobiology of cocaine. Furthermore, these findings suggest that performance can be broken down into meaningful neuropsychological components in very young children.

AB - Patterns of neuropsychological performance on A-not-B, inhibition, motor, cognitive, language, and behavior tasks were examined in 34 toddlers- 17 cocaine-exposed (CE) and 17 nonexposed (NE) controls. CE toddlers exhibited greater perseveration, less inhibition, poorer emotional regulation, and less task orientation relative to NE toddlers. Overall cognitive and language skills and motor impairment status were comparable among CE and NE toddlers. Differences in perseveration, emotional regulation, and task orientation between CE and NE toddlers remained significant after statistically controlling for overall cognitive skill. Prenatal cocaine exposure may impart selective vulnerability for deficits in executive function, inhibition, and emotional regulation in toddlers, perhaps related to the concurrent rapid frontal lobe maturation and the neurobiology of cocaine. Furthermore, these findings suggest that performance can be broken down into meaningful neuropsychological components in very young children.

UR - http://www.scopus.com/inward/record.url?scp=0032933711&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032933711&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0032933711

VL - 15

SP - 447

EP - 460

JO - Developmental Neuropsychology

JF - Developmental Neuropsychology

SN - 8756-5641

IS - 3

ER -