TY - JOUR
T1 - New biologic markers in non-Hodgkin's lymphomas
AU - Grogan, T. M.
AU - Miller, T. P.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 1991
Y1 - 1991
N2 - Recent studies suggest lymphoma surface and nuclear markers may be of both diagnostic and prognostic relevance. Specifically relevant are markers of tumor proliferation (Ki67), histocompatibility antigen (HLA), cell lineage (B versus T), and cell adhesion molecules (CD 22,44,56). Additionally, host response as measured by CD8 may be relevant to lymphoma relapse. Collectively, these tumor and host markers suggest new targets for 'phenotype-directed' therapy.
AB - Recent studies suggest lymphoma surface and nuclear markers may be of both diagnostic and prognostic relevance. Specifically relevant are markers of tumor proliferation (Ki67), histocompatibility antigen (HLA), cell lineage (B versus T), and cell adhesion molecules (CD 22,44,56). Additionally, host response as measured by CD8 may be relevant to lymphoma relapse. Collectively, these tumor and host markers suggest new targets for 'phenotype-directed' therapy.
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U2 - 10.1016/s0889-8588(18)30393-9
DO - 10.1016/s0889-8588(18)30393-9
M3 - Review article
C2 - 1938761
AN - SCOPUS:0025887898
VL - 5
SP - 925
EP - 933
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
SN - 0889-8588
IS - 5
ER -