New developments in the staging of melanoma

Amy C. Baruch, Jiaqi Shi, Yongmei Feng, Mark A. Nelson

Research output: Contribution to journalReview article

7 Scopus citations

Abstract

As the incidence of melanoma increases, so does the search for new staging techniques that may provide important prognostic information and aid in the detection of early metastatic disease. The application of molecular techniques may provide powerful new tools in this search. This review summarizes recent findings obtained by means of conventional RT-PCR, cDNA arrays, and proteomics in the investigation of human melanoma. The molecular tools discussed in this review demonstrate how global transcript and protein analysis might contribute not only to the staging of melanoma, but may hold great promise in improving the diagnosis and treatment of this disease.

Original languageEnglish (US)
Pages (from-to)561-567
Number of pages7
JournalCancer Investigation
Volume23
Issue number6
DOIs
StatePublished - Oct 25 2005

Keywords

  • Melanoma
  • Molecular techniques
  • Proteomics
  • RT-PCR
  • cDNA arrays

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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