New norcucurbitacin and heptanorcucurbitacin glucosides from Fevillea trilobata

Ligia M.M. Valente, A. A.Leslie Gunatilaka, Thomas E. Glass, David G.I. Kingston, Angelo C. Pinto

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

From the MeOH extract of the seeds of Fevillea trilobata (Cucurbitaceae) were isolated fevicordin A glucoside [1], cayaponoside B [2], cayaponoside D [3], a new norcucurbitacin glucoside, and a new heptanorcucurbitacin glucoside. The structure of the new norcucurbitacin glucoside, andirobicin A glucoside, was established as 29-nor-1,2,3,4,5,10-dehydro-25-methoxy-2-O-β-d-glucopyranosyl-3,16α,20R,22ξ-tetrahydroxy-11-oxocucurbit-23-ene [4], and that of the novel heptanorcucurbitacin glucoside, andirobicin B glucoside, as 22,23,24,25,26,27,29-heptanor-1,2,3,4,5,10-dehydro-2-O-β-d-glucopyranosyl-3, 16α-dihydroxycucurbita-11,20-dione [5].

Original languageEnglish (US)
Pages (from-to)1772-1778
Number of pages7
JournalJournal Of Natural Products
Volume56
Issue number10
DOIs
StatePublished - Oct 1993
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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