New strategies for surgical management of ischemic cardiomyopathy

Gorav Ailawadi, Irving L. Kron

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

Ischemic cardiomyopathy affects an estimated 3 million people in the USA and is the most common cause of heart failure. Traditional operations have included heart transplantation, myocardial revascularization, mitral valve repair, left ventricular reconstruction, first-generation left ventricular assist devices and cardiac resynchronization therapy. These operations have become safer in recent times, due to improved technologies. Current technologies and surgical approaches can benefit a significant number of patients. However, there remains a large group of patients in whom traditional approaches can not be offered. Newer generation ventricular assist devices, passive ventricular restraint devices and cellular-based therapies (including skeletal- and bone marrow-derived stem cells) have the potential to be more universal in their applications. Ongoing investigations with each of these modalities will allow surgeons to offer treatment to patients who are not considered surgical candidates at this time.

Original languageEnglish (US)
Pages (from-to)521-530
Number of pages10
JournalExpert review of cardiovascular therapy
Volume6
Issue number4
DOIs
StatePublished - Apr 1 2008
Externally publishedYes

Keywords

  • Coronary artery bypass heart
  • Failure
  • Ischemic cardiomyopathy
  • Left ventricular assist device
  • Left ventricular reconstruction
  • Left ventricular remodeling
  • Mitral repair
  • Stem cells
  • Ventricular restraint device

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

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