No relation between excess fatigue and asymptomatic carotid atherosclerosis

Paul G. McGovern, Eyal Shahar, Aaron R. Folsom, Wayne D. Rosamond

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Prospective studies have reported a positive association of excess fatigue and hopelessness with coronary heart disease mortality; a relation to atherosclerosis has not been investigated. We examined the cross-sectional association of the Maastricht excess fatigue questionnaire with carotid intimal-medial wall thickness among 12,448 coronary heart disease-free individuals age 47-68 years. In age-, race-, and field center-adjusted analyses, we found a strong, positive association between excess fatigue and carotid intimal-medial wall thickness in both sexes. Adjustment for other coronary heart disease risk factors substantially attenuated the relation. Pack-years of smoking was the strongest confounder. Furthermore, there was little association among never-smokers. It appears that the association of excess fatigue with atherosclerotic disease is largely accounted for by established risk factors.

Original languageEnglish (US)
Pages (from-to)638-640
Number of pages3
JournalEpidemiology
Volume7
Issue number6
StatePublished - Nov 1996
Externally publishedYes

Fingerprint

Carotid Artery Diseases
Fatigue
Tunica Intima
Coronary Disease
Atherosclerosis
Smoking
Prospective Studies
Mortality

Keywords

  • carotid atherosclerosis
  • coronary heart disease
  • fatigue
  • gender
  • smoking

ASJC Scopus subject areas

  • Epidemiology

Cite this

McGovern, P. G., Shahar, E., Folsom, A. R., & Rosamond, W. D. (1996). No relation between excess fatigue and asymptomatic carotid atherosclerosis. Epidemiology, 7(6), 638-640.

No relation between excess fatigue and asymptomatic carotid atherosclerosis. / McGovern, Paul G.; Shahar, Eyal; Folsom, Aaron R.; Rosamond, Wayne D.

In: Epidemiology, Vol. 7, No. 6, 11.1996, p. 638-640.

Research output: Contribution to journalArticle

McGovern, PG, Shahar, E, Folsom, AR & Rosamond, WD 1996, 'No relation between excess fatigue and asymptomatic carotid atherosclerosis', Epidemiology, vol. 7, no. 6, pp. 638-640.
McGovern, Paul G. ; Shahar, Eyal ; Folsom, Aaron R. ; Rosamond, Wayne D. / No relation between excess fatigue and asymptomatic carotid atherosclerosis. In: Epidemiology. 1996 ; Vol. 7, No. 6. pp. 638-640.
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