Nonalcoholic fatty liver disease: A comprehensive review of a growing epidemic

Kareem Hassan, Varun Bhalla, Mohammed Ezz El Regal, Hassan H Hassan

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

Nonalcoholic fatty liver disease (NAFLD) is quickly becoming one of the most prominent causes of liver disease worldwide. The increasing incidence of NAFLD is tied to the obesity epidemic and the subsequent metabolic derangements brought along with it. Current efforts to elucidate the mechanism and causes of the disease have answered some questions, but much remains unknown about NAFLD. The aim of this article is to discuss the current knowledge regarding the pathogenesis of the disease, as well as the current and future diagnostic, preventative, and therapeutic options available to clinicians for the management of NAFLD.

Original languageEnglish (US)
Pages (from-to)12082-12101
Number of pages20
JournalWorld Journal of Gastroenterology
Volume20
Issue number34
DOIs
StatePublished - Sep 14 2014

Fingerprint

Liver Diseases
Obesity
Non-alcoholic Fatty Liver Disease
Incidence
Therapeutics

Keywords

  • Diagnosis
  • Imaging
  • Management
  • Metformin
  • Nonalcoholic fatty liver disease
  • Nonalcoholic steatohepatitis
  • Pathogenesis
  • Prevalence
  • Steatohepatitis
  • Thiazolidinedione
  • Treatments
  • Vitamin E

ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

Cite this

Nonalcoholic fatty liver disease : A comprehensive review of a growing epidemic. / Hassan, Kareem; Bhalla, Varun; El Regal, Mohammed Ezz; Hassan, Hassan H.

In: World Journal of Gastroenterology, Vol. 20, No. 34, 14.09.2014, p. 12082-12101.

Research output: Contribution to journalArticle

Hassan, Kareem ; Bhalla, Varun ; El Regal, Mohammed Ezz ; Hassan, Hassan H. / Nonalcoholic fatty liver disease : A comprehensive review of a growing epidemic. In: World Journal of Gastroenterology. 2014 ; Vol. 20, No. 34. pp. 12082-12101.
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