Novel use of insulin in continuous-instillation negative pressure wound therapy as "wound chemotherapy"

Christy L. Scimeca, Manish Bharara, Timothy K. Fisher, Heather Kimbriel, Joseph L Mills, David G Armstrong

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Negative pressure wound therapy (NPWT) is frequently employed in the treatment of complex wounds. A variety of wound chemotherapeutic agents such as insulin, which acts as a growth factor, may prove helpful in treatment as well. We present a case report in which insulin was used as a chemotherapeutic agent in continuous-instillation NPWT. To our knowledge, this is the first report in the literature describing this method of delivery.

Original languageEnglish (US)
Pages (from-to)820-824
Number of pages5
JournalJournal of diabetes science and technology
Volume4
Issue number4
StatePublished - Jul 2010

Fingerprint

Negative-Pressure Wound Therapy
Chemotherapy
Insulin
Drug Therapy
Wounds and Injuries
Intercellular Signaling Peptides and Proteins
Therapeutics

Keywords

  • Diabetic foot ulcers
  • Insulin
  • Negative pressure wound therapy
  • Wound chemotherapy

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Bioengineering
  • Biomedical Engineering

Cite this

Novel use of insulin in continuous-instillation negative pressure wound therapy as "wound chemotherapy". / Scimeca, Christy L.; Bharara, Manish; Fisher, Timothy K.; Kimbriel, Heather; Mills, Joseph L; Armstrong, David G.

In: Journal of diabetes science and technology, Vol. 4, No. 4, 07.2010, p. 820-824.

Research output: Contribution to journalArticle

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