Nutrients and genetic polymorphisms modify arsenic metabolism efficiency

C. Hernández-Alcaraz; R. U. Hernández-Ramírez; A. García-Martínez; A. I. Burguete-García; L. López-Carrillo; M. E. Cebrián; A. J. Gandolfi

doi:10.1201/b16767-185

Nutrients and genetic polymorphisms modify arsenic metabolism efficiency

C. Hernández-Alcaraz, R. U. Hernández-Ramírez, A. García-Martínez, A. I. Burguete-García, L. López-Carrillo, M. E. Cebrián, A. J. Gandolfi

Toxicology, Center for

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The aim of this study was to examine if five single nucleotide polymorphisms involved in one-carbon metabolism are associated with the efficiency of iAs metabolism and if these potential associations are respectively modified by dietary intake of folate-related nutrients. Most of the nutrients and polymorphisms altered the iAs metabolism. Additionally, vitamin B12 and methionine modified the association between FolH1 T223C and MTR A2756G over the iAs metabolism, respectively. Genetic and dietary differences in one-carbon metabolism may jointly account for differences in iAs metabolism.

Original language	English (US)
Title of host publication	One Century of the Discovery of Arsenicosis in Latin America (1914-2014)
Subtitle of host publication	As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment
Publisher	CRC Press/Balkema
Pages	495-497
Number of pages	3
ISBN (Print)	9781138001411
DOIs	https://doi.org/10.1201/b16767-185
State	Published - 2014
Event	5th International Congress on Arsenic in the Environment, As 2014 - Buenos Aires, Argentina Duration: May 11 2014 → May 16 2014

Publication series

Name	One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment

Other

Other	5th International Congress on Arsenic in the Environment, As 2014
Country	Argentina
City	Buenos Aires
Period	5/11/14 → 5/16/14

ASJC Scopus subject areas

Chemical Health and Safety

Access to Document

10.1201/b16767-185

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Hernández-Alcaraz, C., Hernández-Ramírez, R. U., García-Martínez, A., Burguete-García, A. I., López-Carrillo, L., Cebrián, M. E., & Gandolfi, A. J. (2014). Nutrients and genetic polymorphisms modify arsenic metabolism efficiency. In One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment (pp. 495-497). (One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment). CRC Press/Balkema. https://doi.org/10.1201/b16767-185

Nutrients and genetic polymorphisms modify arsenic metabolism efficiency. / Hernández-Alcaraz, C.; Hernández-Ramírez, R. U.; García-Martínez, A.; Burguete-García, A. I.; López-Carrillo, L.; Cebrián, M. E.; Gandolfi, A. J.

One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema, 2014. p. 495-497 (One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hernández-Alcaraz, C, Hernández-Ramírez, RU, García-Martínez, A, Burguete-García, AI, López-Carrillo, L, Cebrián, ME & Gandolfi, AJ 2014, Nutrients and genetic polymorphisms modify arsenic metabolism efficiency. in One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment, CRC Press/Balkema, pp. 495-497, 5th International Congress on Arsenic in the Environment, As 2014, Buenos Aires, Argentina, 5/11/14. https://doi.org/10.1201/b16767-185

Hernández-Alcaraz C, Hernández-Ramírez RU, García-Martínez A, Burguete-García AI, López-Carrillo L, Cebrián ME et al. Nutrients and genetic polymorphisms modify arsenic metabolism efficiency. In One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema. 2014. p. 495-497. (One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment). https://doi.org/10.1201/b16767-185

Hernández-Alcaraz, C. ; Hernández-Ramírez, R. U. ; García-Martínez, A. ; Burguete-García, A. I. ; López-Carrillo, L. ; Cebrián, M. E. ; Gandolfi, A. J. / Nutrients and genetic polymorphisms modify arsenic metabolism efficiency. One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema, 2014. pp. 495-497 (One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment).

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