Nutrients and genetic polymorphisms modify arsenic metabolism efficiency

C. Hernández-Alcaraz, R. U. Hernández-Ramírez, A. García-Martínez, A. I. Burguete-García, L. López-Carrillo, M. E. Cebrián, A. J. Gandolfi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The aim of this study was to examine if five single nucleotide polymorphisms involved in one-carbon metabolism are associated with the efficiency of iAs metabolism and if these potential associations are respectively modified by dietary intake of folate-related nutrients. Most of the nutrients and polymorphisms altered the iAs metabolism. Additionally, vitamin B12 and methionine modified the association between FolH1 T223C and MTR A2756G over the iAs metabolism, respectively. Genetic and dietary differences in one-carbon metabolism may jointly account for differences in iAs metabolism.

Original languageEnglish (US)
Title of host publicationOne Century of the Discovery of Arsenicosis in Latin America (1914-2014)
Subtitle of host publicationAs 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment
PublisherCRC Press/Balkema
Pages495-497
Number of pages3
ISBN (Print)9781138001411
DOIs
StatePublished - Jan 1 2014
Event5th International Congress on Arsenic in the Environment, As 2014 - Buenos Aires, Argentina
Duration: May 11 2014May 16 2014

Publication series

NameOne Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment

Other

Other5th International Congress on Arsenic in the Environment, As 2014
CountryArgentina
CityBuenos Aires
Period5/11/145/16/14

ASJC Scopus subject areas

  • Chemical Health and Safety

Fingerprint Dive into the research topics of 'Nutrients and genetic polymorphisms modify arsenic metabolism efficiency'. Together they form a unique fingerprint.

  • Cite this

    Hernández-Alcaraz, C., Hernández-Ramírez, R. U., García-Martínez, A., Burguete-García, A. I., López-Carrillo, L., Cebrián, M. E., & Gandolfi, A. J. (2014). Nutrients and genetic polymorphisms modify arsenic metabolism efficiency. In One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment (pp. 495-497). (One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment). CRC Press/Balkema. https://doi.org/10.1201/b16767-185