Nutrition and diet in the development of gastrointestinal cancer

Cynthia Thomson, Kaja LeWinn, Tara R. Newton, David S Alberts, Maria Elena Martinez

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Diet plays a role in the prevention and development of gastrointestinal cancers. The majority of available research consists of case - control studies, but the number of clinical trials is growing. The dietary recommendations to reduce gastrointestinal cancer risk include lowering total energy, fat and saturated fat intake; avoidance of grilled and smoked foods; avoidance of alcohol; and increasing intake of fruits, vegetables, and fiber. Studies of esophageal cancer support these dietary approaches, with the exception of dietary fat reduction and increased green tea intake. For gastric cancer, consuming additional fruits and vegetables, including those high in ascorbic acid, may reduce risk, and the capacity for diet to alter Helicobacter pylori infection should be explored. Recent interventional trials do not support a role for high-fiber or low-fat diets in reducing development of colon adenomas, although the evidence does not rule out efficacy at earlier stages of disease. Finally, the evidence for a relationship between pancreatic cancer and diet remains sparse and warrants additional investigation.

Original languageEnglish (US)
Pages (from-to)192-202
Number of pages11
JournalCurrent Oncology Reports
Volume5
Issue number3
StatePublished - May 2003

Fingerprint

Gastrointestinal Neoplasms
Diet
Vegetables
Fruit
Fats
Fat-Restricted Diet
Dietary Fats
Helicobacter Infections
Tea
Esophageal Neoplasms
Pancreatic Neoplasms
Helicobacter pylori
Adenoma
Ascorbic Acid
Stomach Neoplasms
Case-Control Studies
Colon
Alcohols
Clinical Trials
Food

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nutrition and diet in the development of gastrointestinal cancer. / Thomson, Cynthia; LeWinn, Kaja; Newton, Tara R.; Alberts, David S; Martinez, Maria Elena.

In: Current Oncology Reports, Vol. 5, No. 3, 05.2003, p. 192-202.

Research output: Contribution to journalArticle

Thomson, C, LeWinn, K, Newton, TR, Alberts, DS & Martinez, ME 2003, 'Nutrition and diet in the development of gastrointestinal cancer', Current Oncology Reports, vol. 5, no. 3, pp. 192-202.
Thomson, Cynthia ; LeWinn, Kaja ; Newton, Tara R. ; Alberts, David S ; Martinez, Maria Elena. / Nutrition and diet in the development of gastrointestinal cancer. In: Current Oncology Reports. 2003 ; Vol. 5, No. 3. pp. 192-202.
@article{b053857c52fa43a794942b07d6d4a323,
title = "Nutrition and diet in the development of gastrointestinal cancer",
abstract = "Diet plays a role in the prevention and development of gastrointestinal cancers. The majority of available research consists of case - control studies, but the number of clinical trials is growing. The dietary recommendations to reduce gastrointestinal cancer risk include lowering total energy, fat and saturated fat intake; avoidance of grilled and smoked foods; avoidance of alcohol; and increasing intake of fruits, vegetables, and fiber. Studies of esophageal cancer support these dietary approaches, with the exception of dietary fat reduction and increased green tea intake. For gastric cancer, consuming additional fruits and vegetables, including those high in ascorbic acid, may reduce risk, and the capacity for diet to alter Helicobacter pylori infection should be explored. Recent interventional trials do not support a role for high-fiber or low-fat diets in reducing development of colon adenomas, although the evidence does not rule out efficacy at earlier stages of disease. Finally, the evidence for a relationship between pancreatic cancer and diet remains sparse and warrants additional investigation.",
author = "Cynthia Thomson and Kaja LeWinn and Newton, {Tara R.} and Alberts, {David S} and Martinez, {Maria Elena}",
year = "2003",
month = "5",
language = "English (US)",
volume = "5",
pages = "192--202",
journal = "Current Oncology Reports",
issn = "1523-3790",
publisher = "Current Science, Inc.",
number = "3",

}

TY - JOUR

T1 - Nutrition and diet in the development of gastrointestinal cancer

AU - Thomson, Cynthia

AU - LeWinn, Kaja

AU - Newton, Tara R.

AU - Alberts, David S

AU - Martinez, Maria Elena

PY - 2003/5

Y1 - 2003/5

N2 - Diet plays a role in the prevention and development of gastrointestinal cancers. The majority of available research consists of case - control studies, but the number of clinical trials is growing. The dietary recommendations to reduce gastrointestinal cancer risk include lowering total energy, fat and saturated fat intake; avoidance of grilled and smoked foods; avoidance of alcohol; and increasing intake of fruits, vegetables, and fiber. Studies of esophageal cancer support these dietary approaches, with the exception of dietary fat reduction and increased green tea intake. For gastric cancer, consuming additional fruits and vegetables, including those high in ascorbic acid, may reduce risk, and the capacity for diet to alter Helicobacter pylori infection should be explored. Recent interventional trials do not support a role for high-fiber or low-fat diets in reducing development of colon adenomas, although the evidence does not rule out efficacy at earlier stages of disease. Finally, the evidence for a relationship between pancreatic cancer and diet remains sparse and warrants additional investigation.

AB - Diet plays a role in the prevention and development of gastrointestinal cancers. The majority of available research consists of case - control studies, but the number of clinical trials is growing. The dietary recommendations to reduce gastrointestinal cancer risk include lowering total energy, fat and saturated fat intake; avoidance of grilled and smoked foods; avoidance of alcohol; and increasing intake of fruits, vegetables, and fiber. Studies of esophageal cancer support these dietary approaches, with the exception of dietary fat reduction and increased green tea intake. For gastric cancer, consuming additional fruits and vegetables, including those high in ascorbic acid, may reduce risk, and the capacity for diet to alter Helicobacter pylori infection should be explored. Recent interventional trials do not support a role for high-fiber or low-fat diets in reducing development of colon adenomas, although the evidence does not rule out efficacy at earlier stages of disease. Finally, the evidence for a relationship between pancreatic cancer and diet remains sparse and warrants additional investigation.

UR - http://www.scopus.com/inward/record.url?scp=0041735111&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0041735111&partnerID=8YFLogxK

M3 - Article

VL - 5

SP - 192

EP - 202

JO - Current Oncology Reports

JF - Current Oncology Reports

SN - 1523-3790

IS - 3

ER -